TICAM-2 Antibody (G-6): sc-376356

TICAM-2 Antibody (G-6) is a mouse monoclonal IgG1 antibody that detects TICAM-2 in human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). TICAM-2, also known as Toll-interleukin 1 receptor domain-containing adaptor molecule 2, plays a crucial role in the immune response by acting as a bridge between Toll-like receptor 4 (TLR4) and TICAM-1, facilitating the transmission of lipopolysaccharide (LPS) signaling. This interaction is vital for the activation of downstream signaling pathways that lead to the production of pro-inflammatory cytokines, thereby enhancing the body′s ability to respond to bacterial infections. TICAM-2 functions as an essential component of the MyD88-independent signaling pathway, which is critical for the innate immune response, particularly in recognizing and responding to pathogens. Additionally, TICAM-2 shares structural similarities with Mal/TIRAP, another adapter protein that links TLR2 and TLR4 to the MyD88 pathway, highlighting TICAM-2′s importance in the intricate network of immune signaling. Anti-TICAM-2 antibody (G-6) serves as an invaluable tool for researchers studying immune responses and the mechanisms of pathogen recognition.

The preferred TICAM-2 antibody is TICAM-2 Antibody (E-2): sc-376076.