Thy-1/CD90 Antibody (OX7): sc-53116

Thy-1 Antibody (OX7) is a mouse monoclonal IgG1 kappa light chain antibody that detects Thy-1 protein in mouse, rat, and human samples through western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry, and flow cytometry (FCM). Anti-Thy-1 antibody (OX7) comes in non-conjugated and conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates, offering flexibility for diverse experimental applications. Thy-1 protein, also known as CD90, is a glycosylphosphatidylinositol-anchored glycoprotein expressed on thymocytes, neurons, and certain stem cells. Surface expression of Thy-1 enables crucial functions in cell adhesion, signaling, and immune response regulation. Thy-1 monoclonal antibody (OX7) helps researchers study stem cell properties, particularly in hematopoietic stem cells responsible for blood cell formation and immune system function. CD90 interaction with proteins like CD34 aids in identifying specific stem cell subpopulations within bone marrow, contributing to advances in regenerative medicine and transplantation therapies. Anti-Thy-1 antibody (OX7) serves as a key research tool for studying cell surface markers and their biological roles.

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Thy-1/CD90 Antibody (OX7) References:

1. [Phenotypical and functional characterization of leukocytes--the CD-system].  |  Holter, W., et al. 1991. Wien Klin Wochenschr. 103: 247-62. PMID: 2068816
2. Thy-1 (CD90) is an interacting partner for CD97 on activated endothelial cells.  |  Wandel, E., et al. 2012. J Immunol. 188: 1442-50. PMID: 22210915
3. Thy-1 signals through PPARγ to promote lipofibroblast differentiation in the developing lung.  |  Varisco, BM., et al. 2012. Am J Respir Cell Mol Biol. 46: 765-72. PMID: 22268140
4. Thy-1 interaction with Fas in lipid rafts regulates fibroblast apoptosis and lung injury resolution.  |  Liu, X., et al. 2017. Lab Invest. 97: 256-267. PMID: 28165468
5. THY-1 (CD90) expression promotes the growth of gastric cancer cells.  |  Wang, CJ., et al. 2017. Int J Clin Exp Pathol. 10: 9878-9888. PMID: 31966876
6. CD11/CD18 panel report for swine CD workshop.  |  Kim, YB., et al. 1994. Vet Immunol Immunopathol. 43: 289-91. PMID: 7531911
7. Characterization of Thy-1 (CDw90) expression in CD34+ acute leukemia.  |  Holden, JT., et al. 1995. Blood. 86: 60-5. PMID: 7540889
8. The Thy-1 molecule: its properties and functions.  |  Firer, MA., et al. 1995. Isr J Med Sci. 31: 382-6. PMID: 7607863
9. Apoptosis inhibition by anti-M(r) 23,000 (Thy-1) monoclonal antibodies without inducing bcl-2 expression.  |  Fujita, N., et al. 1995. Cell Growth Differ. 6: 355-62. PMID: 7794803
10. Thy1+ bone marrow cells regulate the induction of murine syngeneic graft-versus-host disease.  |  Bryson, JS., et al. 1993. Transplantation. 56: 941-5. PMID: 8105571
11. Expression of Thy-1 antigen (CDw90) on adult acute leukemia blast cells.  |  Campos, L. and Guyotat, D. 1996. Blood. 87: 413-4. PMID: 8547671
12. CD34+Thy-1+Lin- stem cells from mobilized peripheral blood.  |  Murray, LJ., et al. 1996. Leuk Lymphoma. 22: 37-42, follow. 186, color plate I. PMID: 8724526

Monoclonal antibodies for mammalian and non-mammalian protein targets represent essentially all targets covered by polyclonal antibodies. Over 8,300 of our antibodies are offered as ImmunoCruz^® conjugates which eliminates the need for a secondary antibody.

Santa Cruz Biotechnology antibodies have over 360,000 research citations. Anti-Thy-1/CD90 Antibody (OX7) has 30 citations in a variety of scientific publications.

Primary antibodies like Anti-Thy-1/CD90 Antibody (OX7) for mammalian target proteins are recommended for the detection of a range of mammalian species, primarily of mouse, rat and human species. Many mammalian antibodies are also ideal for veterinary research and reactive with ovine, porcine, caprine, feline, canine, bovine and equine protein targets. Santa Cruz Biotechnology primary monoclonal antibodies are suitable for laboratory research applications and are not intended for diagnostic or therapeutic use.

Thy-1/CD90 Antibody (OX7) Specifications

Alternate Product Name: CD90

Product Clone Name: OX7

Classification: Primary Antibody

Clonality: Monoclonal Antibody

Antibody Isotype: IgG₁ kappa light chain

Amino Acids:

Epitope Target: Thy-1

Epitope Species: rat

Product Reactivity/Detection: Thy-1.1 antigenic determinant

Species Reactivity/Detection: mouse, rat, human

Additional Mammalian Reactivity: N/A

Additional Non-Mammalian Reactivity: N/A

Applications: WB, IP, IF, IHC(P), FCM

Vialing Information: Each vial contains 200 µg IgG₁ kappa light chain in 1.0 ml of PBS with < 0.1% sodium azide and 0.1% gelatin

Research Citations: 30 citations in various scientific publications

Available Conjugates/Forms for Thy-1/CD90 Antibody (OX7): AC: Agarose, AF488: Alexa Fluor^® 488, AF546: Alexa Fluor^® 546, AF594: Alexa Fluor^® 594, AF647: Alexa Fluor^® 647, AF680: Alexa Fluor^® 680, AF790: Alexa Fluor^® 790, FITC: Fluoroscein, HRP: Horseradish Peroxidase, PE: Phycoerythrin