THUMPD2 Antibody (D-11): sc-393018
- THUMPD2 Antibody (D-11) is a mouse monoclonal IgG1 κ THUMPD2 antibody, cited in 1 publications, provided at 200 µg/ml
- specific for an epitope mapping between amino acids 417-450 near the C-terminus of THUMPD2 of human origin
- THUMPD2 Antibody (D-11) is recommended for detection of THUMPD2 of mouse, rat and human origin by WB, IP, IF and ELISA
- Anti-THUMPD2 Antibody (D-11) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- TransCruz reagent for ChIP application (sc-393018 X, 200 µg/0.1 ml)
- m-IgG Fc BP-HRP and m-IgG1 BP-HRP are the preferred secondary detection reagents for THUMPD2 Antibody (D-11) for WB applications. These reagents are now offered in bundles with THUMPD2 Antibody (D-11) (see ordering information below).
QUICK LINKS
THUMPD2 Antibody (D-11) is a mouse monoclonal IgG1 kappa light chain antibody that detects THUMPD2 protein of mouse, rat, and human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). anti-THUMPD2 antibody (D-11) is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. THUMPD2, also known as THUMP domain-containing protein 2, consists of 503 amino acids and features a THUMP domain, placing THUMPD2 within the methyltransferase superfamily. THUMPD2 plays a crucial role in RNA metabolism and is involved in the regulation of gene expression, which is vital for maintaining cellular function and responding to environmental changes. THUMPD2 is expressed across a wide range of tissues, including brain, colon, gingiva, heart, kidney, liver, lung, placenta, small intestine, spleen, and thymus, highlighting THUMPD2′s importance in various biological processes. Located on human chromosome 2p22.1, the THUMPD2 gene encodes two alternatively spliced isoforms and is part of a chromosome that comprises approximately 8% of the human genome, which is associated with several genetic diseases. Understanding THUMPD2 function and interactions can provide insights into THUMPD2′s role in health and disease, making THUMPD2 (D-11) monoclonal antibody an essential tool for researchers studying this important protein.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
THUMPD2 Antibody (D-11) References:
- Alstrom syndrome: confirmation of linkage to chromosome 2p12-13 and phenotypic heterogeneity in three affected sibs. | Zumsteg, U., et al. 2000. J Med Genet. 37: E8. PMID: 10882760
- An ATP-binding cassette gene (ABCG5) from the ABCG (White) gene subfamily maps to human chromosome 2p21 in the region of the Sitosterolemia locus. | Shulenin, S., et al. 2001. Cytogenet Cell Genet. 92: 204-8. PMID: 11435688
- Mutation of ALMS1, a large gene with a tandem repeat encoding 47 amino acids, causes Alström syndrome. | Hearn, T., et al. 2002. Nat Genet. 31: 79-83. PMID: 11941370
- Localization, genomic organization, and alternative transcription of a novel human SAM-dependent methyltransferase gene on chromosome 2p22-->p21. | Zhang, Y., et al. 2001. Cytogenet Cell Genet. 95: 146-52. PMID: 12063391
- Mutations in ABCA12 underlie the severe congenital skin disease harlequin ichthyosis. | Kelsell, DP., et al. 2005. Am J Hum Genet. 76: 794-803. PMID: 15756637
- Punctuated duplication seeding events during the evolution of human chromosome 2p11. | Horvath, JE., et al. 2005. Genome Res. 15: 914-27. PMID: 15965031
- An alphoid DNA sequence conserved in all human and great ape chromosomes: evidence for ancient centromeric sequences at human chromosomal regions 2q21 and 9q13. | Baldini, A., et al. 1993. Hum Genet. 90: 577-83. PMID: 8444464
- Mapping a gene involved in regulating dietary cholesterol absorption. The sitosterolemia locus is found at chromosome 2p21. | Patel, SB., et al. 1998. J Clin Invest. 102: 1041-4. PMID: 9727073
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
THUMPD2 Antibody (D-11) | sc-393018 | 200 µg/ml | $322.00 | |||
THUMPD2 Antibody (D-11): m-IgG Fc BP-HRP Bundle | sc-527662 | 200 µg Ab; 10 µg BP | $361.00 | |||
THUMPD2 Antibody (D-11): m-IgG1 BP-HRP Bundle | sc-533035 | 200 µg Ab; 20 µg BP | $361.00 | |||
THUMPD2 Antibody (D-11) X | sc-393018 X | 200 µg/0.1 ml | $322.00 | |||
THUMPD2 Antibody (D-11) AC | sc-393018 AC | 500 µg/ml, 25% agarose | $424.00 | |||
THUMPD2 Antibody (D-11) HRP | sc-393018 HRP | 200 µg/ml | $322.00 | |||
THUMPD2 Antibody (D-11) FITC | sc-393018 FITC | 200 µg/ml | $336.00 | |||
THUMPD2 Antibody (D-11) PE | sc-393018 PE | 200 µg/ml | $349.00 | |||
THUMPD2 Antibody (D-11) Alexa Fluor® 488 | sc-393018 AF488 | 200 µg/ml | $364.00 | |||
THUMPD2 Antibody (D-11) Alexa Fluor® 546 | sc-393018 AF546 | 200 µg/ml | $364.00 | |||
THUMPD2 Antibody (D-11) Alexa Fluor® 594 | sc-393018 AF594 | 200 µg/ml | $364.00 | |||
THUMPD2 Antibody (D-11) Alexa Fluor® 647 | sc-393018 AF647 | 200 µg/ml | $364.00 | |||
THUMPD2 Antibody (D-11) Alexa Fluor® 680 | sc-393018 AF680 | 200 µg/ml | $364.00 | |||
THUMPD2 Antibody (D-11) Alexa Fluor® 790 | sc-393018 AF790 | 200 µg/ml | $364.00 | |||
THUMPD2 (D-11) Neutralizing Peptide | sc-393018 P | 100 µg/0.5 ml | $69.00 |