Thrombospondin 1/2 Antibody (D-9): sc-74538

Thrombospondin 1/2 Antibody (D-9) is a mouse monoclonal IgG1 kappa light chain antibody, engineered to target amino acids 401-700 of human Thrombospondin 1 and Thrombospondin 2, also known as TSP-1/THBS1 and TSP-2/THBS2 respectively. Thrombospondin proteins are essential extracellular matrix glycoproteins that play a critical role in cell-to-cell and cell-to-matrix signaling, facilitating processes such as angiogenesis, wound healing, and tissue remodeling. Located within the extracellular matrix, TSP-1 and TSP-2 are pivotal for regulating cell adhesion, migration, and proliferation, which are vital for maintaining tissue integrity and responding to injury. Anti-Thrombospondin 1/2 antibody (D-9) exhibits strong species reactivity, effectively recognizing Thrombospondin 1 and 2 in mouse, rat, and human samples, making it a versatile tool for applications including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). Thrombospondin 1/2 monoclonal antibody (D-9) allows researchers to investigate the distinct and overlapping functions of TSP-1 and TSP-2 in various biological contexts such as cardiovascular development, cancer progression, and inflammatory responses. Anti-Thrombospondin 1/2 antibody (D-9) is instrumental in advancing research into the extracellular matrix′s role in cellular communication and structural support, thereby contributing to the development of targeted therapeutic strategies for diseases characterized by abnormal cell signaling and matrix interactions. Thrombospondin 1/2 (D-9) monoclonal antibody is an indispensable reagent for scientists exploring the multifaceted roles of Thrombospondin proteins in health and disease.

The preferred Thrombospondin 1 antibody is Thrombospondin 1 Antibody (A6.1): sc-59887.