THNSL2 Antibody (D-8): sc-390627

THNSL2 Antibody (D-8) is a mouse monoclonal IgG1 antibody that detects THNSL2 in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). THNSL2, also known as threonine synthase-like 2 or TSH2, is a 484 amino acid protein that plays a crucial role in amino acid metabolism, particularly in the catabolism of threonine. THNSL2 utilizes pyridoxal phosphate as a cofactor to function as a phospholyase, acting on gamma and beta phosphorylated substrates, and is involved in the degradation of O-phospho-threonine to produce alpha-ketobutyrate, ammonia, and phosphate. THNSL2 regulates threonine levels, which is essential for various biological processes, including protein synthesis and cellular signaling. Additionally, THNSL2 exists in four alternatively spliced isoforms, providing functional diversity that may be critical in different physiological contexts. The gene encoding THNSL2 is located on human chromosome 2p11.2, a region associated with several genetic disorders, highlighting the potential implications of THNSL2 in health and disease. With versatile applications and significant biological role, anti-THNSL2 antibody (D-8) is an invaluable tool for researchers studying amino acid metabolism and related pathways.

The preferred THNSL2 antibody is THNSL2 Antibody (B-4): sc-390395.