THNSL2 Antibody (B-4): sc-390395
- THNSL2 Antibody (B-4) is a mouse monoclonal IgG2b κ THNSL2 antibody provided at 200 µg/ml
- specific for an epitope mapping between amino acids 275-309 within an internal region of THNSL2 of human origin
- THNSL2 Antibody (B-4) is recommended for detection of THNSL2 of mouse, rat and human origin by WB, IP, IF and ELISA
- Anti-THNSL2 Antibody (B-4) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- m-IgG Fc BP-HRP and m-IgG2b BP-HRP are the preferred secondary detection reagents for THNSL2 Antibody (B-4) for WB applications. These reagents are now offered in bundles with THNSL2 Antibody (B-4) (see ordering information below).
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THNSL2 Antibody (B-4) is a mouse monoclonal IgG2b kappa light chain antibody that detects THNSL2 protein of mouse, rat, and human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). THNSL2 (B-4) antibody is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. THNSL2, also known as threonine synthase-like 2 or TSH2, is a 484 amino acid protein that plays a crucial role in amino acid metabolism, particularly in threonine catabolism, an essential amino acid obtained through diet. THNSL2 utilizes pyridoxal phosphate as a cofactor and participates in O-phospho-threonine degradation to produce alpha-ketobutyrate, ammonia, and phosphate, highlighting THNSL2′s importance in maintaining amino acid homeostasis and energy production within cells. THNSL2 gene is located on human chromosome 2p11.2, which contains over 1,400 genes and is associated with various genetic disorders. Multiple alternatively spliced isoforms of THNSL2 emphasize functional diversity and potential regulatory roles in metabolic pathways.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
THNSL2 Antibody (B-4) References:
- Evidence for an ancestral alphoid domain on the long arm of human chromosome 2. | Avarello, R., et al. 1992. Hum Genet. 89: 247-9. PMID: 1587535
- A threonine synthase homolog from a mammalian genome. | Donini, S., et al. 2006. Biochem Biophys Res Commun. 350: 922-8. PMID: 17034760
- Spectrum of ALMS1 variants and evaluation of genotype-phenotype correlations in Alström syndrome. | Marshall, JD., et al. 2007. Hum Mutat. 28: 1114-23. PMID: 17594715
- Origin of human chromosome 2: an ancestral telomere-telomere fusion. | IJdo, JW., et al. 1991. Proc Natl Acad Sci U S A. 88: 9051-5. PMID: 1924367
- A novel T cell cytokine, secreted osteoclastogenic factor of activated T cells, induces osteoclast formation in a RANKL-independent manner. | Rifas, L. and Weitzmann, MN. 2009. Arthritis Rheum. 60: 3324-35. PMID: 19877052
- Time-series gene expression profiles in AGS cells stimulated with Helicobacter pylori. | You, YH., et al. 2010. World J Gastroenterol. 16: 1385-96. PMID: 20238406
- Array-CGH analysis of a cohort of 86 patients with oculoauriculovertebral spectrum. | Rooryck, C., et al. 2010. Am J Med Genet A. 152A: 1984-9. PMID: 20635336
- Bimodal distribution of RNA expression levels in human skeletal muscle tissue. | Mason, CC., et al. 2011. BMC Genomics. 12: 98. PMID: 21299892
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
THNSL2 Antibody (B-4) | sc-390395 | 200 µg/ml | $316.00 | |||
THNSL2 Antibody (B-4): m-IgG Fc BP-HRP Bundle | sc-526154 | 200 µg Ab; 10 µg BP | $354.00 | |||
THNSL2 Antibody (B-4): m-IgG2b BP-HRP Bundle | sc-549686 | 200 µg Ab; 10 µg BP | $354.00 | |||
THNSL2 Antibody (B-4) AC | sc-390395 AC | 500 µg/ml, 25% agarose | $416.00 | |||
THNSL2 Antibody (B-4) HRP | sc-390395 HRP | 200 µg/ml | $316.00 | |||
THNSL2 Antibody (B-4) FITC | sc-390395 FITC | 200 µg/ml | $330.00 | |||
THNSL2 Antibody (B-4) PE | sc-390395 PE | 200 µg/ml | $343.00 | |||
THNSL2 Antibody (B-4) Alexa Fluor® 488 | sc-390395 AF488 | 200 µg/ml | $357.00 | |||
THNSL2 Antibody (B-4) Alexa Fluor® 546 | sc-390395 AF546 | 200 µg/ml | $357.00 | |||
THNSL2 Antibody (B-4) Alexa Fluor® 594 | sc-390395 AF594 | 200 µg/ml | $357.00 | |||
THNSL2 Antibody (B-4) Alexa Fluor® 647 | sc-390395 AF647 | 200 µg/ml | $357.00 | |||
THNSL2 Antibody (B-4) Alexa Fluor® 680 | sc-390395 AF680 | 200 µg/ml | $357.00 | |||
THNSL2 Antibody (B-4) Alexa Fluor® 790 | sc-390395 AF790 | 200 µg/ml | $357.00 | |||
THNSL2 (B-4) Neutralizing Peptide | sc-390395 P | 100 µg/0.5 ml | $68.00 |