TGFα Antibody (134 A): sc-36
- TGFα Antibody (134 A) is a mouse monoclonal IgG1, cited in 38 publications, provided at 100 µg/ml
- raised against recombinant TGFα protein of human origin
- recommended for detection of precursor and mature TGFα of mouse, rat and human origin by WB, IP and IF
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for TGFα Antibody (134 A). This work is in progress.
TGFα Antibody (134 A) is a mouse monoclonal IgG1 antibody that detects transforming growth factor-α (TGFα) in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), and immunofluorescence (IF). TGFα is a crucial 50 amino acid protein that plays a significant role in cell signaling and growth regulation, particularly in the context of cancer. TGFα binds to the epidermal growth factor receptor (EGFR), leading to the activation of downstream signaling pathways that promote cell proliferation and survival. This interaction contributes to the development and progression of various malignancies, making TGFα a potential target for therapeutic intervention. TGFα is secreted by transformed cells, tumors, and some normal adult cells, indicating involvement in both physiological and pathological processes. TGFα bioactivity in the urine of cancer patients underscores relevance as a biomarker for malignancy, suggesting function as an autocrine growth factor that supports tumor growth and maintenance. TGFα mediates critical cellular functions and serves as a vital protein for researchers studying cancer biology and therapeutic strategies.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
TGFα Antibody (134 A) | sc-36 | 100 µg/ml | $316.00 |