TEX28 Antibody (H-3): sc-514450
- TEX28 Antibody (H-3) is a mouse monoclonal IgG1 κ TEX28 antibody provided at 200 µg/ml
- specific for an epitope mapping between amino acids 227-238 within an internal region of TEX28 of mouse origin
- TEX28 Antibody (H-3) is recommended for detection of TEX28 of mouse, rat and human origin by WB, IP, IF and ELISA
- Anti-TEX28 Antibody (H-3) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- m-IgG Fc BP-HRP and m-IgG1 BP-HRP are the preferred secondary detection reagents for TEX28 Antibody (H-3) for WB applications. These reagents are now offered in bundles with TEX28 Antibody (H-3) (see ordering information below).
TEX28 Antibody (H-3) is a mouse monoclonal IgG1 kappa light chain antibody that detects TEX28 protein of mouse, rat, and human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). Anti-TEX28 antibody (H-3) is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. TEX28, also known as testis expressed 28 or fTEX, is a 410 amino acid single-pass membrane protein that plays a crucial role in reproductive biology and is encoded by a gene located on the X chromosome. This gene is associated with MYP1 X-linked myopia phenotypes, and mutations in TEX28 may contribute to color vision disorders. TEX28 localization is particularly significant, as expression occurs primarily in the testis, where TEX28 is believed to be involved in spermatogenesis and male germ cell development. Understanding TEX28 function and expression is essential for elucidating its role in male fertility and potential implications in related disorders. TEX28 consists of five exons that span a considerable distance between protein-coding regions of color pigment genes and a transketolase-related gene, highlighting its complex genetic architecture. Given TEX28 location on the X chromosome, which is critical for sex determination and associated with various genetic conditions, studying TEX28 and its interactions may provide insights into both normal and pathological states of vision and reproduction.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
TEX28 Antibody (H-3) References:
- Features of Turner's syndrome in women with polycystic ovaries. | Givens, JR., et al. 1975. Obstet Gynecol. 45: 619-24. PMID: 1143721
- Analysis of L-cone/M-cone visual pigment gene arrays in females by long-range PCR. | Oda, S., et al. 2003. Vision Res. 43: 489-95. PMID: 12594995
- Overall DNA methylation and chromatin structure of normal and abnormal X chromosomes. | Bernardino-Sgherri, J., et al. 2002. Cytogenet Genome Res. 99: 85-91. PMID: 12900549
- An insertion/deletion TEX28 polymorphism and its application to analysis of red/green visual pigment gene arrays. | Ueyama, H., et al. 2004. J Hum Genet. 49: 548-557. PMID: 15378397
- Novel form of a single X-linked visual pigment gene in a unique dichromatic color-vision defect. | Hayashi, T., et al. 2006. Vis Neurosci. 23: 411-7. PMID: 16961974
- Evaluation of the X-linked high-grade myopia locus (MYP1) with cone dysfunction and color vision deficiencies. | Metlapally, R., et al. 2009. Invest Ophthalmol Vis Sci. 50: 1552-8. PMID: 19098318
- Identification of a gene within the tandem array of red and green color pigment genes. | Hanna, MC., et al. 1997. Genomics. 43: 384-6. PMID: 9268643
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
TEX28 Antibody (H-3) | sc-514450 | 200 µg/ml | $322.00 | |||
TEX28 Antibody (H-3): m-IgG Fc BP-HRP Bundle | sc-527902 | 200 µg Ab; 10 µg BP | $361.00 | |||
TEX28 Antibody (H-3): m-IgG1 BP-HRP Bundle | sc-533275 | 200 µg Ab; 20 µg BP | $361.00 | |||
TEX28 Antibody (H-3) AC | sc-514450 AC | 500 µg/ml, 25% agarose | $424.00 | |||
TEX28 Antibody (H-3) HRP | sc-514450 HRP | 200 µg/ml | $322.00 | |||
TEX28 Antibody (H-3) FITC | sc-514450 FITC | 200 µg/ml | $336.00 | |||
TEX28 Antibody (H-3) PE | sc-514450 PE | 200 µg/ml | $349.00 | |||
TEX28 Antibody (H-3) Alexa Fluor® 488 | sc-514450 AF488 | 200 µg/ml | $364.00 | |||
TEX28 Antibody (H-3) Alexa Fluor® 546 | sc-514450 AF546 | 200 µg/ml | $364.00 | |||
TEX28 Antibody (H-3) Alexa Fluor® 594 | sc-514450 AF594 | 200 µg/ml | $364.00 | |||
TEX28 Antibody (H-3) Alexa Fluor® 647 | sc-514450 AF647 | 200 µg/ml | $364.00 | |||
TEX28 Antibody (H-3) Alexa Fluor® 680 | sc-514450 AF680 | 200 µg/ml | $364.00 | |||
TEX28 Antibody (H-3) Alexa Fluor® 790 | sc-514450 AF790 | 200 µg/ml | $364.00 | |||
TEX28 (H-3) Neutralizing Peptide | sc-514450 P | 100 µg/0.5 ml | $69.00 |