Testosterone 3 CMO Antibody (1.B.154): sc-73143

Testosterone 3 CMO Antibody (1.B.154) is a mouse monoclonal IgG1 antibody that detects Testosterone 3 CMO by enzyme-linked immunosorbent assay (ELISA). Testosterone 3 CMO, also known as Testosterone-3-carboxy-methyl-oxyme, is a steroid hormone from the androgen group primarily secreted by the testis, with smaller amounts produced in the ovaries, adrenal cortices, and placenta, typically derived from cholesterol. Anti-Testosterone 3 CMO antibody (1.B.154) plays a crucial role in studying the development of male external genitalia during fetal development and protein synthesis, which contributes to the greater muscular development observed in males. Testosterone 3 CMO is responsible for the emergence of male secondary sex characteristics, including facial hair and deeper voice, and is vital for overall health and well-being in both males and females. Testosterone 3 CMO undergoes various post-translational modifications, such as phosphorylation and glycosylation, which can influence activity and interactions with other proteins, thereby affecting physiological functions. Several synthetic derivatives of testosterone are utilized in clinical settings to treat advanced disseminated breast cancer in women, particularly when the disease has metastasized to the bones, highlighting the therapeutic significance of this hormone.

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Testosterone 3 CMO Antibody (1.B.154) References:

1. Plasma dihydrotestosterone in normal adult males and its relation to testosterone.  |  Pirke, KM. and Doerr, P. 1975. Acta Endocrinol (Copenh). 79: 357-65. PMID: 1173494
2. Direct radioimmunoassay for the measurement of serum testosterone using 3H as label.  |  Shrivastav, TG. and Kanaujia, PK. 2007. J Immunoassay Immunochem. 28: 127-36. PMID: 17424831
3. Divergent development of testosterone secretion in male zebu (Bos indicus) and crossbred cattle (Bos indicus x Bos taurus) and buffaloes (Bubalus bubalis) during growth.  |  Gulia, S., et al. 2010. Trop Anim Health Prod. 42: 1143-8. PMID: 20213223
4. Steroid analogs inhibit hormone binding by an extract from Nippostrongylus brasiliensis (Nematoda).  |  Majundar, TK., et al. 1987. Comp Biochem Physiol B. 88: 81-4. PMID: 3677617
5. Active immunization of prepubertal boars against testosterone: testicular and endocrine responses at 14 months of age.  |  Thompson, DL., et al. 1985. J Anim Sci. 61: 1498-504. PMID: 3936832
6. A study of 19-O-carboxymethyl ether and 19-hemisuccinate derivatives of testosterone: their immunogenicity and use as iodinated radioligands for radioimmunoassay of testosterone.  |  White, A., et al. 1985. J Steroid Biochem. 23: 981-9. PMID: 4094426
7. Penicillinase as a marker in enzyme-linked immunosorbent assays for steroid hormones.  |  Joshi, UM., et al. 1983. J Steroid Biochem. 19: 419-21. PMID: 6310239
8. Immunization of female rabbits against testosterone stimulates testosterone accumulation by isolated ovarian follicles.  |  Ewaschuk, EJ., et al. 1980. Experientia. 36: 465-6. PMID: 6769697
9. Influence of antisera, purification procedures, and tracers on validity of a testosterone radioimmunoassay.  |  de Gomez, MS., et al. 1981. Ann Clin Biochem. 18: 281-6. PMID: 7305257
10. Effects of active immunization of female rabbits against testosterone.  |  Armstrong, RW., et al. 1978. J Endocrinol. 79: 339-47. PMID: 744928

The preferred Testosterone 3 CMO antibody is Testosterone 3 CMO Antibody (3T16): sc-53455.