TDRD10 Antibody (C-7): sc-514046

TDRD10 Antibody (C-7) is a mouse monoclonal IgM antibody that detects TDRD10 of mouse, rat, and human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). Anti-TDRD10 antibody (C-7) is available as the non-conjugated form. TDRD10, also known as Tudor domain-containing protein 10, is a 366 amino acid protein characterized by one RNA recognition motif (RRM) domain and one Tudor domain, which are crucial for RNA binding and protein-protein interactions. TDRD10 is primarily located in the cytoplasm and is involved in gene expression regulation and RNA metabolism, making TDRD10 essential for various cellular processes, including spermatogenesis and genomic stability maintenance. The TDRD10 gene, which maps to human chromosome 1q21.3, encodes two alternatively spliced isoforms, highlighting potential complexity in function and regulation. Chromosome 1 harbors approximately 3,000 genes and is associated with numerous diseases, including rare genetic disorders and various cancers, underscoring the importance of studying TDRD10 in understanding cellular mechanisms and disease pathology.

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TDRD10 Antibody (C-7) References:

1. The Stickler syndrome: case reports and literature review.  |  Bowling, EL., et al. 2000. Optometry. 71: 177-82. PMID: 10970261
2. Gaucher disease and parkinsonism: a phenotypic and genotypic characterization.  |  Tayebi, N., et al. 2001. Mol Genet Metab. 73: 313-21. PMID: 11509013
3. Exclusion of an extracolonic disease modifier locus on chromosome 1p33-36 in a large Swiss familial adenomatous polyposis kindred.  |  Plasilova, M., et al. 2004. Eur J Hum Genet. 12: 365-71. PMID: 14735163
4. Identification of risk and age-at-onset genes on chromosome 1p in Parkinson disease.  |  Oliveira, SA., et al. 2005. Am J Hum Genet. 77: 252-64. PMID: 15986317
5. Fas-associated factor 1 and Parkinson's disease.  |  Betarbet, R., et al. 2008. Neurobiol Dis. 31: 309-15. PMID: 18573343
6. Analysis of the vitreous membrane in a case of type 1 Stickler syndrome.  |  Yokoi, T., et al. 2009. Graefes Arch Clin Exp Ophthalmol. 247: 715-8. PMID: 19089441
7. Identification of a modifier gene locus on chromosome 1p35-36 in familial adenomatous polyposis.  |  Dobbie, Z., et al. 1997. Hum Genet. 99: 653-7. PMID: 9150735
8. Mutation of a gene encoding a protein with extracellular matrix motifs in Usher syndrome type IIa.  |  Eudy, JD., et al. 1998. Science. 280: 1753-7. PMID: 9624053
9. Isolation of a gene encoding a novel member of the nuclear receptor superfamily from the critical region of Usher syndrome type IIa at 1q41.  |  Eudy, JD., et al. 1998. Genomics. 50: 382-4. PMID: 9676434

Monoclonal antibodies for mammalian and non-mammalian protein targets represent essentially all targets covered by polyclonal antibodies. Over 8,300 of our antibodies are offered as ImmunoCruz^® conjugates which eliminates the need for a secondary antibody.

Santa Cruz Biotechnology antibodies have over 360,000 research citations. Anti-TDRD10 Antibody (C-7) has 0 citations in a variety of scientific publications.

Primary antibodies like Anti-TDRD10 Antibody (C-7) for mammalian target proteins are recommended for the detection of a range of mammalian species, primarily of mouse, rat and human species. Many mammalian antibodies are also ideal for veterinary research and reactive with ovine, porcine, caprine, feline, canine, bovine and equine protein targets. Santa Cruz Biotechnology primary monoclonal antibodies are suitable for laboratory research applications and are not intended for diagnostic or therapeutic use.

TDRD10 Antibody (C-7) Specifications

Alternate Product Name: TDRD10

Product Clone Name: C-7

Classification: Primary Antibody

Clonality: Monoclonal Antibody

Antibody Isotype: IgM kappa light chain

Amino Acids: 1-23

Epitope Target: TDRD10

Epitope Species: human

Product Reactivity/Detection: TDRD10

Species Reactivity/Detection: mouse, rat, human

Additional Mammalian Reactivity: N/A

Additional Non-Mammalian Reactivity: N/A

Applications: WB, IP, IF, ELISA

Vialing Information: Each vial contains 200 µg IgM kappa light chain in 1.0 ml of PBS with < 0.1% sodium azide and 0.1% gelatin

Research Citations: 0 citations in various scientific publications

Available Conjugates/Forms for TDRD10 Antibody (C-7): P: Blocking Peptide, X: TransCruz Reagent