TCR V β 11 Antibody (KT11): sc-59383
- TCR V β 11 Antibody (KT11) is a rat monoclonal IgG2b provided at 200 µg/ml
- recommended for detection of TCR V β 11 of mouse origin by FCM
- available conjugated to FITC for IF, IHC(P) and FCM
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for TCR V β 11 Antibody (KT11). This work is in progress.
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TCR V β 11 Antibody (KT11) is a rat monoclonal IgG2b antibody that detects T cell receptor V β 11 (TCR V β 11) in mouse samples through flow cytometry. TCR V β 11 plays a crucial role in the immune response by recognizing specific antigens presented by major histocompatibility complex (MHC) molecules, which is essential for the activation and proliferation of T cells. TCR V β 11 is primarily located on the surface of T cells, where TCR V β 11 forms part of the T cell receptor complex, allowing T cells to distinguish between self and non-self antigens. TCR V β 11′s ability to bind to a diverse array of antigens is vital for the adaptive immune system, as this binding enables the body to mount effective responses against various pathogens. Additionally, TCR V β 11 is involved in the somatic recombination process that generates a diverse T cell receptor repertoire, ensuring that T cells can recognize a wide range of antigens. Understanding TCR V β 11′s function and location is important for developing targeted immunotherapies and enhancing our knowledge of T cell-mediated immunity. TCR V β 11 Antibody (KT11) is an invaluable tool for researchers studying T cell activation and differentiation in mouse models.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
TCR V β 11 Antibody (KT11) References:
- Modification of T-cell receptor Vbeta repertoire in response to allergen stimulation in peanut allergy. | Bakakos, P., et al. 2001. J Allergy Clin Immunol. 107: 1089-94. PMID: 11398090
- The immunogenic peptide for Th1 development. | Takatsu, K. and Kariyone, A. 2003. Int Immunopharmacol. 3: 783-800. PMID: 12781696
- Immunogenicity of Peptide-25 of Ag85B in Th1 development: role of IFN-gamma. | Kariyone, A., et al. 2003. Int Immunol. 15: 1183-94. PMID: 13679388
- Patients with X-linked lymphoproliferative disease due to BIRC4 mutation have normal invariant natural killer T-cell populations. | Marsh, RA., et al. 2009. Clin Immunol. 132: 116-23. PMID: 19398375
- Interleukin 2 abrogates the nonresponsive state of T cells expressing a forbidden T cell receptor repertoire and induces autoimmune disease in neonatally thymectomized mice. | Andreu-Sánchez, JL., et al. 1991. J Exp Med. 173: 1323-9. PMID: 2033367
- CD3γ-independent pathways in TCR-mediated signaling in mature T and iNKT lymphocytes. | Reiné, J., et al. 2011. Cell Immunol. 271: 62-6. PMID: 21764047
- Mycobacterium tuberculosis-specific memory NKT cells in patients with tuberculous pleurisy. | Li, Z., et al. 2014. J Clin Immunol. 34: 979-90. PMID: 25190196
- A Critical Role for TGF-β/Fc and Nonlytic IL-2/Fc Fusion Proteins in Promoting Chimerism and Donor-Specific Tolerance. | Xu, H., et al. 2017. Transplantation. 101: 294-301. PMID: 27306533
- Immune response during tumor therapy with antibody-superantigen fusion proteins. | Rosendahl, A., et al. 1996. Int J Cancer. 68: 109-13. PMID: 8895549
- Prevention of superantigen-induced down-regulation of T-cell mediated cytotoxic activity by IL-2 in vivo. | Belfrage, H., et al. 1997. Immunology. 90: 183-8. PMID: 9135545
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
TCR V β 11 Antibody (KT11) | sc-59383 | 200 µg/ml | $322.00 | |||
TCR V β11 Antibody (KT11) FITC | sc-59383 FITC | 200 µg/ml | $336.00 |