TARM1 Antibody (B-4): sc-514218

TARM1 Antibody (B-4) is a mouse monoclonal IgM antibody that detects TARM1 of mouse and rat origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). Anti-TARM1 antibody (B-4) is available as the non-conjugated format. TARM1, also known as T-cell-interacting, activating receptor on myeloid cells protein 1 or OLT-2 (OSCAR-like transcript-2 protein), is a 271 amino acid single-pass type I membrane protein characterized by two immunoglobulin-like C2-type domains and exists in two alternatively spliced isoforms. TARM1 plays a crucial role in immune responses by facilitating interactions between T cells and myeloid cells, which is essential for the activation and regulation of immune functions. Understanding TARM1 function is particularly important as research may influence the development of therapeutic strategies for immune-related diseases and conditions. The gene encoding TARM1 spans 11,434 bases and is located on human chromosome 19q13.42, a region known for high gene density and association with various genetic disorders. Chromosome 19 harbors a diverse array of genes, including those related to the immunoglobulin superfamily, which are vital for immune system functioning.

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TARM1 Antibody (B-4) References:

1. C-CAM1, a candidate tumor suppressor gene, is abnormally expressed in primary lung cancers.  |  Wang, L., et al. 2000. Clin Cancer Res. 6: 2988-93. PMID: 10955775
2. The genomic context of natural killer receptor extended gene families.  |  Trowsdale, J., et al. 2001. Immunol Rev. 181: 20-38. PMID: 11513141
3. Complete germline deletion of the STK11 gene in a family with Peutz-Jeghers syndrome.  |  Le Meur, N., et al. 2004. Eur J Hum Genet. 12: 415-8. PMID: 14970844
4. Comparative human-mouse-rat sequence analysis of the ICAM gene cluster on HSA 19p13.2 and a 185-kb porcine region from SSC 2q.  |  Leeb, T. and Müller, M. 2004. Gene. 343: 239-44. PMID: 15588578
5. The extended human leukocyte receptor complex: diverse ways of modulating immune responses.  |  Barrow, AD. and Trowsdale, J. 2008. Immunol Rev. 224: 98-123. PMID: 18759923
6. Breakpoint characterization of a novel approximately 59 kb genomic deletion on 19q13.42 in autosomal-dominant retinitis pigmentosa with incomplete penetrance.  |  Köhn, L., et al. 2009. Eur J Hum Genet. 17: 651-5. PMID: 19050727
7. Gene organization of the pregnancy-specific glycoprotein region on human chromosome 19: assembly and analysis of a 700-kb cosmid contig spanning the region.  |  Olsen, A., et al. 1994. Genomics. 23: 659-68. PMID: 7851895
8. The pregnancy-specific glycoprotein (PSG) gene cluster on human chromosome 19: fine structure of the 11 PSG genes and identification of 6 new genes forming a third subgroup within the carcinoembryonic antigen (CEA) family.  |  Teglund, S., et al. 1994. Genomics. 23: 669-84. PMID: 7851896

Monoclonal antibodies for mammalian and non-mammalian protein targets represent essentially all targets covered by polyclonal antibodies. Over 8,300 of our antibodies are offered as ImmunoCruz^® conjugates which eliminates the need for a secondary antibody.

Santa Cruz Biotechnology antibodies have over 360,000 research citations. Anti-TARM1 Antibody (B-4) has 0 citations in a variety of scientific publications.

Primary antibodies like Anti-TARM1 Antibody (B-4) for mammalian target proteins are recommended for the detection of a range of mammalian species, primarily of mouse, rat and human species. Many mammalian antibodies are also ideal for veterinary research and reactive with ovine, porcine, caprine, feline, canine, bovine and equine protein targets. Santa Cruz Biotechnology primary monoclonal antibodies are suitable for laboratory research applications and are not intended for diagnostic or therapeutic use.

TARM1 Antibody (B-4) Specifications

Alternate Product Name: TARM1

Product Clone Name: B-4

Classification: Primary Antibody

Clonality: Monoclonal Antibody

Antibody Isotype: IgM kappa light chain

Amino Acids: 237-259

Epitope Target: TARM1

Epitope Species: mouse

Product Reactivity/Detection: TARM1

Species Reactivity/Detection: mouse, rat

Additional Mammalian Reactivity: N/A

Additional Non-Mammalian Reactivity: N/A

Applications: WB, IP, IF, ELISA

Vialing Information: Each vial contains 200 µg IgM kappa light chain in 1.0 ml of PBS with < 0.1% sodium azide and 0.1% gelatin

Research Citations: 0 citations in various scientific publications

Available Conjugates/Forms for TARM1 Antibody (B-4): P: Blocking Peptide