suprabasin Antibody (H-9): sc-515037
- suprabasin Antibody (H-9) is a mouse monoclonal IgG1 λ suprabasin antibody, cited in 1 publications, provided at 200 µg/ml
- specific for an epitope mapping between amino acids 219-231 near the C-terminus of suprabasin of human origin
- suprabasin Antibody (H-9) is recommended for detection of suprabasin of mouse, rat and human origin by WB, IP, IF and ELISA
- Anti-suprabasin Antibody (H-9) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- m-IgGλ BP-HRP (mouse IgGλ binding protein-HRP) is the preferred secondary detection reagent for suprabasin Antibody (H-9) for WB applications. This reagent is now offered in a bundle with suprabasin Antibody (H-9) (see ordering information below). For additional m-IgGλ BP conjugates see our complete list of Mouse IgG Binding Proteins.
QUICK LINKS
SEE ALSO...
Suprabasin Antibody (H-9) is a mouse monoclonal IgG1 antibody that detects suprabasin protein of mouse, rat, and human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). Anti-suprabasin antibody (H-9) is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. Suprabasin (SBSN) is a 247 amino acid secreted protein that plays a crucial role in epidermal differentiation, particularly in keratinocyte maturation. SBSN is predominantly expressed in tissues such as the uterus, skin, thymus, and esophagus, and is encoded by a gene located on human chromosome 19q13.12. Suprabasin′s significance lies in regulating keratinocyte behavior, which is essential for maintaining skin integrity and function. Additionally, chromosome 19 houses a variety of important genes, including those associated with immunoglobulin superfamily members and various genetic disorders, highlighting suprabasin′s broader implications in cellular processes and potential impact on skin-related diseases.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
suprabasin Antibody (H-9) References:
- The genomic context of natural killer receptor extended gene families. | Trowsdale, J., et al. 2001. Immunol Rev. 181: 20-38. PMID: 11513141
- Suprabasin, a novel epidermal differentiation marker and potential cornified envelope precursor. | Park, GT., et al. 2002. J Biol Chem. 277: 45195-202. PMID: 12228223
- Complete germline deletion of the STK11 gene in a family with Peutz-Jeghers syndrome. | Le Meur, N., et al. 2004. Eur J Hum Genet. 12: 415-8. PMID: 14970844
- Identification of novel keratinocyte-secreted peptides dermokine-alpha/-beta and a new stratified epithelium-secreted protein gene complex on human chromosome 19q13.1. | Matsui, T., et al. 2004. Genomics. 84: 384-97. PMID: 15234001
- Identification of a conserved cluster of skin-specific genes encoding secreted proteins. | Moffatt, P., et al. 2004. Gene. 334: 123-31. PMID: 15256262
- Comparative human-mouse-rat sequence analysis of the ICAM gene cluster on HSA 19p13.2 and a 185-kb porcine region from SSC 2q. | Leeb, T. and Müller, M. 2004. Gene. 343: 239-44. PMID: 15588578
- Large-scale identification of human genes implicated in epidermal barrier function. | Toulza, E., et al. 2007. Genome Biol. 8: R107. PMID: 17562024
- The extended human leukocyte receptor complex: diverse ways of modulating immune responses. | Barrow, AD. and Trowsdale, J. 2008. Immunol Rev. 224: 98-123. PMID: 18759923
- Gene organization of the pregnancy-specific glycoprotein region on human chromosome 19: assembly and analysis of a 700-kb cosmid contig spanning the region. | Olsen, A., et al. 1994. Genomics. 23: 659-68. PMID: 7851895
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
suprabasin Antibody (H-9) | sc-515037 | 200 µg/ml | $316.00 | |||
suprabasin Antibody (H-9): m-IgGλ BP-HRP Bundle | sc-524912 | 200 µg Ab, 40 µg BP | $354.00 | |||
suprabasin Antibody (H-9) AC | sc-515037 AC | 500 µg/ml, 25% agarose | $416.00 | |||
suprabasin Antibody (H-9) HRP | sc-515037 HRP | 200 µg/ml | $316.00 | |||
suprabasin Antibody (H-9) FITC | sc-515037 FITC | 200 µg/ml | $330.00 | |||
suprabasin Antibody (H-9) PE | sc-515037 PE | 200 µg/ml | $343.00 | |||
suprabasin Antibody (H-9) Alexa Fluor® 488 | sc-515037 AF488 | 200 µg/ml | $357.00 | |||
suprabasin Antibody (H-9) Alexa Fluor® 546 | sc-515037 AF546 | 200 µg/ml | $357.00 | |||
suprabasin Antibody (H-9) Alexa Fluor® 594 | sc-515037 AF594 | 200 µg/ml | $357.00 | |||
suprabasin Antibody (H-9) Alexa Fluor® 647 | sc-515037 AF647 | 200 µg/ml | $357.00 | |||
suprabasin Antibody (H-9) Alexa Fluor® 680 | sc-515037 AF680 | 200 µg/ml | $357.00 | |||
suprabasin Antibody (H-9) Alexa Fluor® 790 | sc-515037 AF790 | 200 µg/ml | $357.00 | |||
suprabasin (H-9) Neutralizing Peptide | sc-515037 P | 100 µg/0.5 ml | $68.00 |