SUMO-3 Antibody (76AT630.91.31) is a mouse monoclonal IgG1 antibody engineered to recognize human SUMO-3, also known as Small Ubiquitin-like Modifier 3 or SUMO3. SUMO-3 monoclonal antibody (76AT630.91.31) is validated for use in western blotting (WB), immunoprecipitation (IP), and enzyme-linked immunosorbent assay (ELISA), ensuring robust performance across multiple experimental platforms. SUMO-3 is a critical member of the SUMO protein family, which plays a pivotal role in the post-translational modification process known as sumoylation. Unlike ubiquitination, which primarily targets proteins for degradation, sumoylation by SUMO-3 regulates a diverse range of cellular functions including nuclear transport, transcriptional regulation, apoptosis, and protein stability. These regulatory mechanisms are essential for maintaining cellular homeostasis, responding to stress, and controlling gene expression. The unconjugated form of SUMO-3 predominantly localizes within the nucleus, where SUMO-3 interacts with various nuclear proteins to influence critical biological processes. By modulating these interactions, SUMO-3 is integral to processes such as DNA repair, cell cycle progression, and the regulation of transcription factors. Anti-SUMO-3 antibody (76AT630.91.31) provides researchers with a reliable tool to investigate the intricate roles of SUMO-3 in cellular dynamics and disease pathology, facilitating advancements in understanding the molecular underpinnings of various biological systems.
Ordering Information
Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
SUMO-3 Antibody (76AT630.91.31) | sc-130884 | 100 µg/ml | $316.00 |