SULT1E1 Antibody (E-12): sc-376009
- SULT1E1 Antibody (E-12) is a mouse monoclonal IgG1 κ SULT1E1 antibody, cited in 6 publications, provided at 200 µg/ml
- raised against amino acids 3 mapping within an internal region of SULT1E1 of human origin
- SULT1E1 Antibody (E-12) is recommended for detection of SULT1E1 of mouse, rat and human origin by WB, IP, IF, IHC(P) and ELISA
- Anti-SULT1E1 Antibody (E-12) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for SULT1E1 Antibody (E-12). This work is in progress.
SULT1E1 Antibody (E-12) is a mouse monoclonal IgG1 kappa light chain antibody that detects SULT1E1 protein of mouse, rat, and human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), and enzyme-linked immunosorbent assay (ELISA). Anti-SULT1E1 antibody (E-12) is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. SULT1E1, also known as STE, is a 294 amino acid member of the sulfotransferase family, primarily localized in the cytoplasm and expressed in the intestine, liver, and kidney. SULT1E1 plays a crucial role in regulating estrogen receptor levels by catalyzing the sulfate conjugation of free estradiol, thus influencing hormonal balance and potentially impacting processes such as cell proliferation and differentiation. SULT1E1′s homodimeric structure is essential for enzymatic activity, and defects in SULT1E1 have been linked to an increased risk of endometrial cancer, highlighting SULT1E1′s significance in tumorigenesis and importance in various biological contexts.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
SULT1E1 Antibody (E-12) References:
- Sulfotransferase catalyzing sulfation of heterocyclic amines. | Yamazoe, Y., et al. 1999. Cancer Lett. 143: 103-7. PMID: 10503886
- Association between functional genetic polymorphisms of human sulfotransferases 1A1 and 1A2. | Engelke, CE., et al. 2000. Pharmacogenetics. 10: 163-9. PMID: 10762004
- Structure and localization of the human SULT1B1 gene: neighborhood to SULT1E1 and a SULT1D pseudogene. | Meinl, W. and Glatt, H. 2001. Biochem Biophys Res Commun. 288: 855-62. PMID: 11688987
- Sulfotransferase 1A2*2 is a risk factor for early-onset breast cancer. | Hou, MF., et al. 2002. Int J Mol Med. 10: 609-12. PMID: 12373301
- Estrogen sulfation genes, hormone replacement therapy, and endometrial cancer risk. | Rebbeck, TR., et al. 2006. J Natl Cancer Inst. 98: 1311-20. PMID: 16985250
- Expression of sulfotransferase 1E1 in human prostate as studied by in situ hybridization and immunocytochemistry. | Takase, Y., et al. 2007. Prostate. 67: 405-9. PMID: 17187396
- Structural and chemical profiling of the human cytosolic sulfotransferases. | Allali-Hassani, A., et al. 2007. PLoS Biol. 5: e97. PMID: 17425406
- CYP1A1, SULT1A1, and SULT1E1 polymorphisms are risk factors for endometrial cancer susceptibility. | Hirata, H., et al. 2008. Cancer. 112: 1964-73. PMID: 18318428
- Arylamine activating sulfotransferase in liver. | Nagata, K., et al. 1997. Mutat Res. 376: 267-72. PMID: 9202764
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
SULT1E1 Antibody (E-12) | sc-376009 | 200 µg/ml | $322.00 | |||
SULT1E1 Antibody (E-12) AC | sc-376009 AC | 500 µg/ml, 25% agarose | $424.00 | |||
SULT1E1 Antibody (E-12) HRP | sc-376009 HRP | 200 µg/ml | $322.00 | |||
SULT1E1 Antibody (E-12) FITC | sc-376009 FITC | 200 µg/ml | $336.00 | |||
SULT1E1 Antibody (E-12) PE | sc-376009 PE | 200 µg/ml | $349.00 | |||
SULT1E1 Antibody (E-12) Alexa Fluor® 488 | sc-376009 AF488 | 200 µg/ml | $364.00 | |||
SULT1E1 Antibody (E-12) Alexa Fluor® 546 | sc-376009 AF546 | 200 µg/ml | $364.00 | |||
SULT1E1 Antibody (E-12) Alexa Fluor® 594 | sc-376009 AF594 | 200 µg/ml | $364.00 | |||
SULT1E1 Antibody (E-12) Alexa Fluor® 647 | sc-376009 AF647 | 200 µg/ml | $364.00 | |||
SULT1E1 Antibody (E-12) Alexa Fluor® 680 | sc-376009 AF680 | 200 µg/ml | $364.00 | |||
SULT1E1 Antibody (E-12) Alexa Fluor® 790 | sc-376009 AF790 | 200 µg/ml | $364.00 |