

SULT1 Antibody (3F10) is a mouse monoclonal IgG2b antibody that detects SULT1 in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), and enzyme-linked immunosorbent assay (ELISA). SULT1, a member of the sulfotransferase superfamily, plays a crucial role in the metabolism of xenobiotics and endogenous compounds by catalyzing the sulfate conjugation of various substrates, which is essential for their detoxification and elimination from the body. Anti-SULT1 antibody (3F10) enables research into cancer prevention, as high activity levels of SULT1 have been associated with increased protection against carcinogens linked to colorectal cancer. Notably, the SULT1A1 allele exhibits heightened activity in elderly individuals, suggesting that SULT1 may help mitigate cellular and tissue damage associated with aging. The specificity of SULT1 for certain substrates, including carcinogenic heterocyclic amines and phenolic compounds, underscores its significance in pharmacogenomics and personalized medicine, as variations in SULT1 activity can influence individual responses to drugs and environmental toxins. SULT1 monoclonal antibody (3F10) serves as an invaluable tool for researchers investigating the role of sulfotransferases in health and disease, providing insights into the mechanisms of detoxification and the potential for therapeutic interventions.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
SULT1 Antibody (3F10) | sc-59705 | 100 µg/ml | $322.00 |