Sucralose (CAS 56038-13-2)
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Sucralose is a synthetic organochlorine sweetener used extensively in food science research due to its non-caloric nature and high sweetness profile. In research, it is studied for its stability under various processing conditions, including high temperatures and varying pH levels, which is significant for its incorporation into diverse food products. Researchers also explore its interaction with other food ingredients and its potential impact on the sensory properties of food, such as taste and texture. Additionally, Sucralose is used in analytical studies to develop and refine detection methods in complex matrices, enhancing food quality control and safety. Environmental scientists study the breakdown products and persistence of Sucralose in water treatment systems, as it is a relevant compound for understanding anthropogenic effects on water quality and aquatic ecosystems.
Sucralose (CAS 56038-13-2) References
- Sucralose: lack of effects on sperm glycolysis and reproduction in the rat. | Kille, JW., et al. 2000. Food Chem Toxicol. 38 Suppl 2: S19-29. PMID: 10882815
- Sucralose: assessment of teratogenic potential in the rat and the rabbit. | Kille, JW., et al. 2000. Food Chem Toxicol. 38 Suppl 2: S43-52. PMID: 10882817
- Specific interactions between diphenhydramine and alpha-helical poly(glutamic acid)--a new ion-pairing complex for taste masking and pH-controlled diphenhydramine release. | Agresti, C., et al. 2008. Eur J Pharm Biopharm. 70: 226-33. PMID: 18514496
- Luminal regulation of normal and neoplastic human EC cell serotonin release is mediated by bile salts, amines, tastants, and olfactants. | Kidd, M., et al. 2008. Am J Physiol Gastrointest Liver Physiol. 295: G260-72. PMID: 18556422
- Consumption of SC45647 and sucralose by rats selectively bred for high and low saccharin intake. | Dess, NK., et al. 2009. Chem Senses. 34: 211-20. PMID: 19129238
- Rats display a robust bimodal preference profile for sucralose. | Loney, GC., et al. 2011. Chem Senses. 36: 733-45. PMID: 21653913
- Sucralose, a synthetic organochlorine sweetener: overview of biological issues. | Schiffman, SS. and Rother, KI. 2013. J Toxicol Environ Health B Crit Rev. 16: 399-451. PMID: 24219506
- Sucralose administered in feed, beginning prenatally through lifespan, induces hematopoietic neoplasias in male swiss mice. | M, S., et al. 2016. Int J Occup Environ Health. 22: 7-17. PMID: 27078173
- A histological assessment of effects of sucralose on liver of albino rats. | Dhurandhar, D., et al. 2018. Morphologie. 102: 197-204. PMID: 30078469
- Intestinal Metabolism and Bioaccumulation of Sucralose In Adipose Tissue In The Rat. | Bornemann, V., et al. 2018. J Toxicol Environ Health A. 81: 913-923. PMID: 30130461
- Natural and Artificial Sweeteners and High Fat Diet Modify Differential Taste Receptors, Insulin, and TLR4-Mediated Inflammatory Pathways in Adipose Tissues of Rats. | Sánchez-Tapia, M., et al. 2019. Nutrients. 11: PMID: 31010163
- Aspartame and Sucralose-induced Fatty Changes in Rat Liver. | Haq, N., et al. 2019. J Coll Physicians Surg Pak. 29: 848-851. PMID: 31455480
- Sucralose can improve glucose tolerance and upregulate expression of sweet taste receptors and glucose transporters in an obese rat model. | Qian, C., et al. 2021. Eur J Nutr. 60: 1809-1817. PMID: 32860125
- The effect of aspartame and sucralose intake on body weight measures and blood metabolites: role of their form (solid and/or liquid) of ingestion. | Ragi, ME., et al. 2022. Br J Nutr. 128: 352-360. PMID: 34420538
- Low Doses of Sucralose Alter Fecal Microbiota in High-Fat Diet-Induced Obese Rats. | Zhang, M., et al. 2021. Front Nutr. 8: 787055. PMID: 35028307
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Sucralose, 100 mg | sc-222332 | 100 mg | $130.00 | |||
Sucralose, 1 g | sc-222332A | 1 g | $454.00 |