Streptococcus agalactiae Antibody (1.B.501): sc-73072

Streptococcus agalactiae Antibody (1.B.501) is a mouse monoclonal IgG1 antibody that detects Streptococcus agalactiae protein by enzyme-linked immunosorbent assay (ELISA). Anti-Streptococcus agalactiae antibody (1.B.501) is available as a non-conjugated format. Streptococcus agalactiae is a Gram-positive bacterium causing severe infections like bacteremia and meningitis, particularly affecting immunocompromised individuals and neonates. This bacterium contains group B Lancefield antigens and typically inhabits the healthy gut and female urogenital tract. A key feature of Streptococcus agalactiae is a polysaccharide antiphagocytic capsule serving as a major virulence factor. This capsule protects against phagocytosis by immune cells while stimulating host immune response, contributing significantly to disease progression. During the perinatal period, capsule presence can trigger serious infections in newborns, including neonatal pneumonia, sepsis, and meningitis, often manifesting as poor feeding, vomiting, fever, and irritability. Research on capsule function in Streptococcus agalactiae pathogenicity remains essential for developing effective treatments and vaccines.

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Streptococcus agalactiae Antibody (1.B.501) References:

1. Use of a serotype-specific DNA microarray for identification of group B Streptococcus (Streptococcus agalactiae).  |  Wen, L., et al. 2006. J Clin Microbiol. 44: 1447-52. PMID: 16597875
2. Understanding the bacterial polysaccharide antigenicity of Streptococcus agalactiae versus Streptococcus pneumoniae.  |  Kadirvelraj, R., et al. 2006. Proc Natl Acad Sci U S A. 103: 8149-54. PMID: 16705032
3. [Streptococcus agalactiae in nonpregnant adults].  |  Toumi, A., et al. 2006. Tunis Med. 84: 161-4. PMID: 16755956
4. [Vaginal colonization of the Streptococcus agalactiae in pregnant woman in Tunisia: risk factors and susceptibility of isolates to antibiotics].  |  Ferjani, A., et al. 2006. Bull Soc Pathol Exot. 99: 99-102. PMID: 16821439
5. Identification of novel genomic islands coding for antigenic pilus-like structures in Streptococcus agalactiae.  |  Rosini, R., et al. 2006. Mol Microbiol. 61: 126-41. PMID: 16824100
6. Transport of multidrug resistance substrates by the Streptococcus agalactiae hemolysin transporter.  |  Gottschalk, B., et al. 2006. J Bacteriol. 188: 5984-92. PMID: 16885467
7. Loss of catabolic function in Streptococcus agalactiae strains and its association with neonatal meningitis.  |  Domelier, AS., et al. 2006. J Clin Microbiol. 44: 3245-50. PMID: 16954255
8. Regulation of cytotoxin expression by converging eukaryotic-type and two-component signalling mechanisms in Streptococcus agalactiae.  |  Rajagopal, L., et al. 2006. Mol Microbiol. 62: 941-57. PMID: 17005013
9. Evaluation of a multiplex PCR-based reverse line blot-hybridization assay for identification of serotype and surface protein antigens of Streptococcus agalactiae.  |  Zeng, X., et al. 2006. J Clin Microbiol. 44: 3822-5. PMID: 17021119

Monoclonal antibodies for mammalian and non-mammalian protein targets represent essentially all targets covered by polyclonal antibodies. Over 8,300 of our antibodies are offered as ImmunoCruz^® conjugates which eliminates the need for a secondary antibody.

Santa Cruz Biotechnology antibodies have over 360,000 research citations. Anti-Streptococcus agalactiae Antibody (1.B.501) has 3 citations in a variety of scientific publications.

Primary antibodies for mammalian target proteins are recommended for the detection of a range of mammalian species, primarily of mouse, rat and human species. Many mammalian antibodies are also ideal for veterinary research and reactive with ovine, porcine, caprine, feline, canine, bovine and equine protein targets. Santa Cruz Biotechnology primary monoclonal antibodies are suitable for laboratory research applications and are not intended for diagnostic or therapeutic use.

Streptococcus agalactiae Antibody (1.B.501) Specifications

Alternate Product Name: Streptococcus agalactiae

Product Clone Name: 1.B.501

Classification: Primary Antibody

Clonality: Monoclonal Antibody

Antibody Isotype: IgG₁

Amino Acids:

Epitope Target: Streptococcus agalactiae

Epitope Species: Streptococcus agalactiae

Product Reactivity/Detection: Streptococcus agalactiae

Species Reactivity/Detection: Streptococcus agalactiae

Additional Mammalian Reactivity: N/A

Additional Non-Mammalian Reactivity: Streptococcus agalactiae

Applications: ELISA

Vialing Information: Each vial contains 100 µg IgG₁ in 1.0 ml of PBS with < 0.1% sodium azide and 0.1% gelatin

Research Citations: 3 citations in various scientific publications

Available Conjugates/Forms for Streptococcus agalactiae Antibody (1.B.501): N/A