Streptococcus agalactiae Inhibitors
Streptococcus agalactiae Inhibitors is not a specific or defined chemical class like, for instance, beta-lactams or fluoroquinolones. Instead, it's a general term that would encompass any chemical compounds known to inhibit the growth or activity of the bacterium Streptococcus agalactiae, commonly known as Group B Streptococcus (GBS). The diverse chemicals that inhibit GBS span various chemical classes, each possessing unique structural features and modes of action. As such, discussing them collectively as a single "class" might be somewhat misleading.
The mechanisms by which these inhibitors function can be diverse. Some target the bacterial cell wall, compromising its structural integrity and inhibitng the bacteria from maintaining a necessary barrier against its environment. For example, β-lactam antibiotics, which include penicillins and cephalosporins, achieve their inhibitory effects by disrupting the synthesis of the bacterial cell wall. Others, like fluoroquinolones, target the bacterial DNA gyrase and topoisomerase IV, crucial enzymes for DNA replication, transcription, repair, and recombination. Macrolides and aminoglycosides, on the other hand, exert their inhibitory effects by targeting the bacterial ribosome, hindering its ability to synthesize proteins vital for the bacterium's survival and function. Each inhibitor has a unique mechanism, yet all converge on the same outcome: the inhibition of GBS growth or activity. The diversity in chemical structures and mechanisms of action highlights the complexity of bacterial biology and the various pathways that can be targeted to achieve inhibition.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Penicillin G sodium salt | 69-57-8 | sc-257971 sc-257971A sc-257971B sc-257971C sc-257971D | 1 mg 10 mg 1 g 5 g 100 g | $26.00 $37.00 $47.00 $171.00 $265.00 | 1 | |
Penicillin G is a β-lactam antibiotic that inhibits bacterial cell wall synthesis by binding to and inactivating penicillin-binding proteins (PBPs). This leads to compromised cell wall integrity and bacterial cell death. | ||||||
Ampicillin | 69-53-4 | sc-210812 sc-210812A sc-210812B sc-210812C sc-210812D | 100 mg 1 g 5 g 25 g 100 g | $31.00 $101.00 $153.00 $115.00 $408.00 | 11 | |
Ampicillin is also a β-lactam antibiotic. It works similarly to Penicillin G by binding to PBPs, inhibiting cell wall synthesis and eventually causing bacterial lysis. | ||||||
Clindamycin | 18323-44-9 | sc-337636A sc-337636B sc-337636C sc-337636 | 25 mg 50 mg 100 mg 1 g | $156.00 $374.00 $572.00 $825.00 | 2 | |
Clindamycin inhibits protein synthesis in bacteria by binding to the 50S ribosomal subunit. This blocks the formation of the initiation complex and the subsequent elongation of the peptide chain. | ||||||
Levofloxacin | 100986-85-4 | sc-252953 sc-252953B sc-252953A | 10 mg 250 mg 1 g | $40.00 $46.00 $54.00 | 3 | |
Levofloxacin is a fluoroquinolone antibiotic. It inhibits bacterial DNA gyrase and topoisomerase IV, enzymes vital for DNA replication, transcription, repair, and recombination, leading to bacterial cell death. | ||||||
Erythromycin | 114-07-8 | sc-204742 sc-204742A sc-204742B sc-204742C | 5 g 25 g 100 g 1 kg | $57.00 $245.00 $831.00 $1331.00 | 4 | |
Erythromycin inhibits bacterial protein synthesis by binding to the 50S ribosomal subunit, blocking the translocation of the growing peptide chain from the A-site to the P-site on the ribosome. | ||||||
Rifampicin | 13292-46-1 | sc-200910 sc-200910A sc-200910B sc-200910C | 1 g 5 g 100 g 250 g | $97.00 $328.00 $676.00 $1467.00 | 6 | |
Rifampin inhibits bacterial RNA synthesis by binding to the β subunit of the bacterial RNA polymerase, thereby preventing the initiation of transcription. | ||||||
Tetracycline | 60-54-8 | sc-205858 sc-205858A sc-205858B sc-205858C sc-205858D | 10 g 25 g 100 g 500 g 1 kg | $63.00 $94.00 $270.00 $417.00 $634.00 | 6 | |
Tetracycline inhibits bacterial protein synthesis by binding to the 30S ribosomal subunit, preventing the binding of aminoacyl-tRNA to the mRNA-ribosome complex. | ||||||
Chloramphenicol | 56-75-7 | sc-3594 | 25 g | $90.00 | 10 | |
Chloramphenicol inhibits bacterial protein synthesis by binding to the 50S ribosomal subunit, specifically inhibiting the peptidyl transferase activity and blocking peptide bond formation. | ||||||
Gentamicin sulfate | 1405-41-0 | sc-203334 sc-203334A sc-203334F sc-203334B sc-203334C sc-203334D sc-203334E | 1 g 5 g 50 g 100 g 1 kg 2.5 kg 7.5 kg | $56.00 $179.00 $509.00 $725.00 $1836.00 $2652.00 $6248.00 | 3 | |
Gentamicin, an aminoglycoside antibiotic, binds to the 30S ribosomal subunit of bacteria, causing misreading of mRNA and inhibition of protein synthesis, leading to bacterial cell death. | ||||||