Stat1 Antibody (SM2): sc-51702
- Stat1 Antibody (SM2) is a mouse monoclonal IgG1, cited in 2 publications, provided at 100 µg/ml
- raised against human STAT 1 peptide sequence 8-23 (QLDSKFLEQVHQLYD)
- recommended for detection of Stat1 of mouse, rat and human origin by WB and IP
- See Stat1 (C-136): sc-464 for Stat1 antibody conjugates, including AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 and 790.
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for Stat1 Antibody (SM2). This work is in progress.
Stat1 Antibody (SM2) is a mouse monoclonal IgG1 light chain antibody that detects STAT1 in mouse, rat, and human samples through applications such as western blotting (WB) and immunoprecipitation (IP). STAT1 plays a crucial role in the immune response by mediating the effects of interferons, which are vital for the regulation of genes involved in antiviral defense and immune system modulation. Upon activation by interferons, STAT1 forms a heterodimer with STAT2, contributing to the formation of the ISGF3 transcription factor complex that drives the expression of interferon-stimulated genes. This process is essential for the host′s ability to respond to viral infections and other immune challenges. STAT1 is predominantly located in the cytoplasm and translocates to the nucleus upon activation, where STAT1 binds to specific DNA sequences to regulate gene transcription. Proper functioning of STAT1 is critical, as dysregulation can lead to immune deficiencies or contribute to the development of autoimmune diseases. Anti-STAT1 antibody (SM2) is an invaluable tool for researchers studying the intricate signaling pathways involved in immune responses and the role of STAT1 in various biological processes.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Stat1 Antibody (SM2) | sc-51702 | 100 µg/ml | $322.00 |