ss/ds DNA marker Antibody (1.BB.26): sc-73061
- ss/ds DNA marker Antibody (1.BB.26) is a mouse monoclonal IgM provided at 100 µg/ml
- raised against calf thymus DNA
- recommended for detection of single or double stranded eukaryotic DNA of mammalian origin by WB
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for ss/ds DNA marker Antibody (1.BB.26). This work is in progress.
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ss/ds DNA marker Antibody (1.BB.26) is a mouse monoclonal IgM antibody that detects deoxyribonucleic acid (DNA) in mammalian species through western blotting (WB). ss/ds DNA marker (1.BB.26) antibody plays a crucial role in distinguishing between single-stranded and double-stranded DNA, which is essential for various molecular biology applications, including the study of DNA replication, repair, and transcription. Anti-ss/ds DNA marker antibody (1.BB.26) enables differentiation between these two forms of DNA, as single-stranded DNA is often an intermediate during processes such as replication and transcription, while double-stranded DNA serves as the stable storage form of genetic information. Understanding the dynamics between these two states can provide insights into cellular processes and the mechanisms of diseases, including cancer, where DNA damage and repair pathways are frequently disrupted. ss/ds DNA marker monoclonal antibody (1.BB.26) serves as an invaluable tool for researchers investigating the complexities of DNA biology and its implications in health and disease.
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LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
ss/ds DNA marker Antibody (1.BB.26) References:
- Peptide mimicking antigenic and immunogenic epitope of double-stranded DNA in systemic lupus erythematosus. | Sun, Y., et al. 2001. Int Immunol. 13: 223-32. PMID: 11157855
- Visualizing recombination intermediates with single-stranded DNA curtains. | Qi, Z. and Greene, EC. 2016. Methods. 105: 62-74. PMID: 27038747
- Single-stranded DNA damage: Protecting the single-stranded DNA from chemical attack. | Anindya, R. 2020. DNA Repair (Amst). 87: 102804. PMID: 31981739
- Hypermutation in single-stranded DNA. | Saini, N. and Gordenin, DA. 2020. DNA Repair (Amst). 91-92: 102868. PMID: 32438271
- Generation of HBsAg DNA aptamer using modified cell-based SELEX strategy. | Mirian, M., et al. 2021. Mol Biol Rep. 48: 139-146. PMID: 33400073
- Generating single-stranded DNA circles with minimal resources. | Ford, A., et al. 2021. MethodsX. 8: 101300. PMID: 34434820
- Single-Molecule Methods for Investigating the Double-Stranded DNA Bendability. | Yeou, S. and Lee, NK. 2022. Mol Cells. 45: 33-40. PMID: 34470919
- Co-condensation of proteins with single- and double-stranded DNA. | Renger, R., et al. 2022. Proc Natl Acad Sci U S A. 119: e2107871119. PMID: 35238639
- Alignment of helicases on single-stranded DNA increases activity. | Ozaslan, D., et al. 2022. Methods Enzymol. 672: 29-54. PMID: 35934480
- A topoisomerase II inhibitor, NK109, induces DNA single- and double-strand breaks and apoptosis. | Fukuda, M., et al. 1996. Jpn J Cancer Res. 87: 1086-91. PMID: 8957068
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
ss/ds DNA marker Antibody (1.BB.26) | sc-73061 | 100 µg/ml | $322.00 |