SRP14 Antibody (H-11): sc-377007
- SRP14 Antibody (H-11) is a mouse monoclonal IgG3 κ provided at 200 µg/ml
- specific for an epitope mapping between amino acids 35-73 within an internal region of SRP14 of human origin
- recommended for detection of SRP14 of mouse, rat and human origin by WB, IP, IF and ELISA
- m-IgG3 BP-HRP is the preferred secondary detection reagent for SRP14 Antibody (H-11) for WB applications. This reagent is now offered in a bundle with SRP14 Antibody (H-11) (see ordering information below).
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SRP14 Antibody (H-11) is a mouse monoclonal IgG3 antibody that detects SRP14 in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). SRP14 plays a critical role in the function of the signal recognition particle (SRP), a ribonucleoprotein complex essential for targeting nascent proteins to the endoplasmic reticulum, thereby facilitating proper protein synthesis and localization. SRP14 is located in the cytoplasm and is integral to the formation of the SRP complex, where SRP14 interacts with SRP9 to stabilize the SRP RNA structure. This interaction is vital for the transcription, maturation, and nucleolar localization of SRP RNA, ensuring that proteins are accurately directed to their functional sites within the cell. The importance of SRP14 in maintaining cellular homeostasis and protein trafficking underscores SRP14′s relevance in studies of protein synthesis and related disorders. Anti-SRP14 antibody (H-11) is an invaluable tool for researchers investigating the mechanisms of protein targeting and the implications of SRP dysfunction in various diseases.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
SRP14 Antibody (H-11) | sc-377007 | 200 µg/ml | $316.00 | |||
SRP14 Antibody (H-11): m-IgG3 BP-HRP Bundle | sc-550465 | 200 µg Ab; 40 µg BP | $354.00 | |||
SRP14 (H-11) Neutralizing Peptide | sc-377007 P | 100 µg/0.5 ml | $68.00 |