SREBP-2 Antibody (C-6): sc-271615
- SREBP-2 Antibody (C-6) is a mouse monoclonal IgG2a κ, cited in 11 publications, provided at 200 µg/ml
- raised against amino acids 812-975 of SREBP-2 of human origin
- recommended for detection of SREBP-2 of mouse, rat and human origin by WB, IP, IF, IHC(P) and ELISA
- See SREBP-2 (1C6): sc-13552 for SREBP-2 antibody conjugates, including AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 and 790.
- m-IgG Fc BP-HRP is the preferred secondary detection reagent for SREBP-2 Antibody (C-6) for WB and IHC(P) applications. This reagent is now offered in a bundle with SREBP-2 Antibody (C-6) (see ordering information below).
SREBP-2 Antibody (C-6) is a mouse monoclonal IgG2a antibody that detects SREBP-2 in mouse, rat, and human samples through various applications including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry, and enzyme-linked immunosorbent assay (ELISA). SREBP-2, or Sterol Regulatory Element-Binding Protein 2, plays a crucial role in lipid metabolism by regulating the expression of genes involved in cholesterol synthesis and uptake, which is vital for maintaining cellular and systemic cholesterol homeostasis. SREBP-2 is primarily located in the endoplasmic reticulum and the nucleus, where SREBP-2 undergoes proteolytic cleavage to release its active form that translocates to the nucleus to activate target gene transcription. Proper functioning of SREBP-2 is essential, as dysregulation can lead to cholesterol-related disorders, including atherosclerosis and other cardiovascular diseases. Anti-SREBP-2 antibody (C-6) is an invaluable tool for researchers studying lipid metabolism and its implications in health and disease, providing insights into the molecular mechanisms that govern cholesterol regulation.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
SREBP-2 Antibody (C-6) | sc-271615 | 200 µg/ml | $322.00 | |||
SREBP-2 Antibody (C-6): m-IgG Fc BP-HRP Bundle | sc-540254 | 200 µg Ab; 10 µg BP | $361.00 |