Date published: 2025-10-21

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SREBP-2 Antibodies

Santa Cruz Biotechnology features a diverse variety of SREBP-2 monoclonal antibodies for advanced research in lipid metabolism and cellular regulation. SREBP-2 Antibodies are validated for multiple applications, including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), flow cytometry (FCM), and enzyme-linked immunosorbent assay (ELISA). Sterol regulatory element-binding protein 2 (SREBP-2) plays a crucial role in cholesterol homeostasis and lipid biosynthesis, making it a significant target for studies related to cardiovascular diseases and metabolic disorders. By regulating the expression of genes involved in cholesterol uptake and synthesis, SREBP-2 is essential for maintaining cellular lipid levels and overall metabolic health. Understanding SREBP-2 function can provide insights into the mechanisms underlying various diseases, including atherosclerosis and diabetes. Researchers can explore the relationship between SREBP-2 and cholesterol metabolism through detailed molecular studies. Advanced imaging techniques using SREBP-2 monoclonal antibodies enable visualization of protein localization and trafficking within cells. Comprehensive analysis of SREBP-2 activity helps reveal its role in maintaining lipid homeostasis. Santa Cruz Biotechnology monoclonal antibodies for SREBP-2 support researchers worldwide in advancing our understanding of lipid metabolism and its impact on human health.

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SREBP-2 Antibodies

Empty Table HeaderProduct NameCATALOG #ISOTYPEEPITOPEAPPLICATIONSSpeciesCitationsRATING

SREBP-2 Antibody (1C6)

sc-13552mouse IgG1 κ833-1141 (h)WB, IP, IFm, r, h
80
(25)

SREBP-2 Antibody (A-12)

sc-271616mouse IgG2a κ812-975 (h)WB, IP, IF, IHC(P), ELISAm, r, h
15
(9)

SREBP-2 Antibody (C-6)

sc-271615mouse IgG2a κ812-975 (h)WB, IP, IF, IHC(P), ELISAm, r, h
11
(2)

SREBP-2 CRISPR Knockout, HDR and Double Nickase Plasmids

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

SREBP-2 CRISPR/Cas9 KO Plasmid (h2)

sc-400575-KO-2hGene KnockoutGFP0
(0)

SREBP-2 HDR Plasmid (h2)

sc-400575-HDR-2hHomology Directed RepairPuromycin0
(0)

SREBP-2 Double Nickase Plasmid (h)

sc-400575-NIChGene KnockoutPuromycin0
(0)

SREBP-2 Double Nickase Plasmid (h2)

sc-400575-NIC-2hGene KnockoutPuromycin0
(0)

SREBP-2 CRISPR/Cas9 KO Plasmid (m)

sc-423153mGene KnockoutGFP0
(0)

SREBP-2 HDR Plasmid (m)

sc-423153-HDRmHomology Directed RepairPuromycin0
(0)

SREBP-2 Double Nickase Plasmid (m)

sc-423153-NICmGene KnockoutPuromycin0
(0)

SREBP-2 Double Nickase Plasmid (m2)

sc-423153-NIC-2mGene KnockoutPuromycin0
(0)

SREBP-2 CRISPR Activation Products

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

SREBP-2 CRISPR Activation Plasmid (h)

sc-400575-ACThGene ActivationPuro, Blast, Hygro0
(0)

SREBP-2 CRISPR Activation Plasmid (h2)

sc-400575-ACT-2hGene ActivationPuro, Blast, Hygro0
(0)

SREBP-2 Lentiviral Activation Particles (h)

sc-400575-LAChGene ActivationPuro, Blast, Hygro0
(0)

SREBP-2 Lentiviral Activation Particles (h2)

sc-400575-LAC-2hGene ActivationPuro, Blast, Hygro0
(0)

SREBP-2 CRISPR Activation Plasmid (m)

sc-423153-ACTmGene ActivationPuro, Blast, Hygro0
(0)

SREBP-2 CRISPR Activation Plasmid (m2)

sc-423153-ACT-2mGene ActivationPuro, Blast, Hygro0
(0)

SREBP-2 Lentiviral Activation Particles (m)

sc-423153-LACmGene ActivationPuro, Blast, Hygro0
(0)

SREBP-2 Lentiviral Activation Particles (m2)

sc-423153-LAC-2mGene ActivationPuro, Blast, Hygro0
(0)

SREBP-2 siRNA, shRNA Plasmid and shRNA Lentiviral Particle Gene Silencers

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

SREBP-2 siRNA (h)

sc-36559hGene SilencingN/A
11
(0)

SREBP-2 shRNA Plasmid (h)

sc-36559-SHhGene SilencingPuromycin
11
(0)

SREBP-2 shRNA (h) Lentiviral Particles

sc-36559-VhGene SilencingPuromycin
11
(0)

SREBP-2 siRNA (m)

sc-36560mGene SilencingN/A0
(0)

SREBP-2 shRNA Plasmid (m)

sc-36560-SHmGene SilencingPuromycin0
(0)

SREBP-2 shRNA (m) Lentiviral Particles

sc-36560-VmGene SilencingPuromycin0
(0)