Spir-1 Antibody (4C5): sc-517039
- Spir-1 Antibody (4C5) is a mouse monoclonal IgG2a κ, cited in 1 publications, provided at 100 µg/ml
- raised against amino acids 482-583 representing partial length Spir-1 of human origin
- recommended for detection of Spir-1 of human origin by WB, IP and ELISA
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for Spir-1 Antibody (4C5). This work is in progress.
QUICK LINKS
Spir-1 Antibody (4C5) is a mouse monoclonal IgG2a antibody that detects Spir-1 in human samples through applications such as western blotting (WB), immunoprecipitation (IP), and enzyme-linked immunosorbent assay (ELISA). Spir-1, also known as spire homolog 1, is a 756 amino acid protein that plays a crucial role as an actin nucleation factor, facilitating the growth of new actin filaments and participating in vesicle transport processes. This function is vital for maintaining cellular structure and dynamics, as actin filaments are essential for various cellular activities, including motility, division, and intracellular transport. Spir-1 is localized to the cytoskeleton and the perinuclear region of the cytoplasm, where Spir-1 effectively links intracellular transport mechanisms with actin organization, thereby influencing cellular morphology and function. Spir-1 is encoded by a gene located on human chromosome 18, which is associated with several genetic disorders, including Trisomy 18 and various forms of cancer. Notably, multiple isoforms of Spir-1 arise from alternative splicing, allowing for functional diversity that may be critical in different cellular contexts. Anti-Spir-1 antibody (4C5) is an essential tool for researchers studying the intricate roles of actin dynamics in health and disease.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Spir-1 Antibody (4C5) | sc-517039 | 100 µg/ml | $322.00 |