Date published: 2025-12-8

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Spir-1 Antibodies

Santa Cruz Biotechnology delivers a wide array of Spir-1 monoclonal antibodies for research focused on understanding Spir-1 protein function. Spir-1 monoclonal antibodies are suitable for multiple applications, including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), flow cytometry (FCM), and enzyme-linked immunosorbent assay (ELISA). Spir-1, also known as the Spire protein, serves as a key regulator in actin filament assembly and influences essential cellular processes such as cell motility and morphogenesis. The involvement of Spir-1 in cytoskeletal dynamics makes it particularly relevant for research in developmental biology and cancer studies. Investigating Spir-1 function provides valuable insights into cellular behavior mechanisms and disease pathology. Researchers can utilize Spir-1 monoclonal antibodies to examine protein expression patterns across different tissue types and cellular compartments. Advanced visualization techniques with horseradish peroxidase (HRP), phycoerythrin (PE), and fluorescein isothiocyanate (FITC) conjugates enable precise detection and localization of Spir-1. Understanding Spir-1's role in cellular processes can reveal new therapeutic targets and treatment strategies. Santa Cruz Biotechnology monoclonal antibodies support the scientific community in advancing knowledge of cellular mechanisms and disease progression through reliable and specific detection of Spir-1.

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Spir-1 Antibodies

Empty Table HeaderProduct NameCATALOG #ISOTYPEEPITOPEAPPLICATIONSSpeciesCitationsRATING

Spir-1 Antibody (H-1)

sc-515448mouse IgG1 κ411-557 (h)WB, IP, IF, ELISAm, r, h
1
(1)

Spir-1 Antibody (4C5)

sc-517039mouse IgG2a κ482-583 (h)WB, IP, ELISAh
1
(0)

Spir-1 CRISPR Knockout, HDR and Double Nickase Plasmids

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

Spir-1 CRISPR/Cas9 KO Plasmid (h)

sc-405257hGene KnockoutGFP0
(0)

Spir-1 HDR Plasmid (h)

sc-405257-HDRhHomology Directed RepairPuromycin0
(0)

Spir-1 Double Nickase Plasmid (h)

sc-405257-NIChGene KnockoutPuromycin0
(0)

Spir-1 Double Nickase Plasmid (h2)

sc-405257-NIC-2hGene KnockoutPuromycin0
(0)

Spir-1 CRISPR/Cas9 KO Plasmid (m)

sc-426949mGene KnockoutGFP0
(0)

Spir-1 HDR Plasmid (m)

sc-426949-HDRmHomology Directed RepairPuromycin0
(0)

Spir-1 Double Nickase Plasmid (m)

sc-426949-NICmGene KnockoutPuromycin0
(0)

Spir-1 Double Nickase Plasmid (m2)

sc-426949-NIC-2mGene KnockoutPuromycin0
(0)

Spir-1 CRISPR Activation Products

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

Spir-1 CRISPR Activation Plasmid (h)

sc-405257-ACThGene ActivationPuro, Blast, Hygro0
(0)

Spir-1 CRISPR Activation Plasmid (h2)

sc-405257-ACT-2hGene ActivationPuro, Blast, Hygro0
(0)

Spir-1 Lentiviral Activation Particles (h)

sc-405257-LAChGene ActivationPuro, Blast, Hygro0
(0)

Spir-1 Lentiviral Activation Particles (h2)

sc-405257-LAC-2hGene ActivationPuro, Blast, Hygro0
(0)

Spir-1 CRISPR Activation Plasmid (m)

sc-426949-ACTmGene ActivationPuro, Blast, Hygro0
(0)

Spir-1 CRISPR Activation Plasmid (m2)

sc-426949-ACT-2mGene ActivationPuro, Blast, Hygro0
(0)

Spir-1 Lentiviral Activation Particles (m)

sc-426949-LACmGene ActivationPuro, Blast, Hygro0
(0)

Spir-1 Lentiviral Activation Particles (m2)

sc-426949-LAC-2mGene ActivationPuro, Blast, Hygro0
(0)

Spir-1 siRNA, shRNA Plasmid and shRNA Lentiviral Particle Gene Silencers

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

Spir-1 siRNA (h)

sc-76567hGene SilencingN/A0
(0)

Spir-1 shRNA Plasmid (h)

sc-76567-SHhGene SilencingPuromycin0
(0)

Spir-1 shRNA (h) Lentiviral Particles

sc-76567-VhGene SilencingPuromycin0
(0)

Spir-1 siRNA (m)

sc-153771mGene SilencingN/A0
(0)

Spir-1 shRNA Plasmid (m)

sc-153771-SHmGene SilencingPuromycin0
(0)

Spir-1 shRNA (m) Lentiviral Particles

sc-153771-VmGene SilencingPuromycin0
(0)