SPATC1L Antibody (C-4): sc-390764
- SPATC1L Antibody (C-4) is a mouse monoclonal IgG1 κ SPATC1L antibody provided at 200 µg/ml
- specific for an epitope mapping between amino acids 161-195 of SPATC1L of human origin
- SPATC1L Antibody (C-4) is recommended for detection of SPATC1L of mouse, rat and human origin by WB, IP, IF and ELISA
- Anti-SPATC1L Antibody (C-4) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- m-IgG1 BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for SPATC1L Antibody (C-4) for WB applications. These reagents are now offered in bundles with SPATC1L Antibody (C-4) (see ordering information below).
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SPATC1L Antibody (C-4) is a mouse monoclonal IgG1 kappa light chain antibody that detects SPATC1L protein of mouse, rat, and human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). Anti-SPATC1L antibody (C-4) is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. SPATC1L plays a crucial role in cellular processes, particularly in regulating cell proliferation and differentiation, which are vital for maintaining normal tissue homeostasis and function. Dysregulation of SPATC1L has been implicated in various diseases, including certain cancers, where altered expression can lead to uncontrolled cell growth. Understanding SPATC1L function is essential for developing targeted therapies and improving treatment outcomes for conditions associated with dysfunction.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
SPATC1L Antibody (C-4) References:
- Molecular cytogenetic dissection of human chromosomes 3 and 21 evolution. | Müller, S., et al. 2000. Proc Natl Acad Sci U S A. 97: 206-11. PMID: 10618396
- Primary and secondary transcriptional effects in the developing human Down syndrome brain and heart. | Mao, R., et al. 2005. Genome Biol. 6: R107. PMID: 16420667
- BACE2, as a novel APP theta-secretase, is not responsible for the pathogenesis of Alzheimer's disease in Down syndrome. | Sun, X., et al. 2006. FASEB J. 20: 1369-76. PMID: 16816112
- The discovery and mapping to chromosome 21 of the Alzheimer's amyloid gene: history revised. | Robakis, NK. 2006. J Alzheimers Dis. 10: 453-5. PMID: 17183160
- Acute myeloid leukemia with the 8q22;21q22 translocation: secondary mutational events and alternative t(8;21) transcripts. | Peterson, LF., et al. 2007. Blood. 110: 799-805. PMID: 17412887
- Classification of human chromosome 21 gene-expression variations in Down syndrome: impact on disease phenotypes. | Aït Yahya-Graison, E., et al. 2007. Am J Hum Genet. 81: 475-91. PMID: 17701894
- DYRK1A-mediated hyperphosphorylation of Tau. A functional link between Down syndrome and Alzheimer disease. | Ryoo, SR., et al. 2007. J Biol Chem. 282: 34850-7. PMID: 17906291
- Exclusion of KCNE1 (IsK) as a candidate gene for Jervell and Lange-Nielsen syndrome. | Tesson, F., et al. 1996. J Mol Cell Cardiol. 28: 2051-5. PMID: 8899564
- IsK and KvLQT1: mutation in either of the two subunits of the slow component of the delayed rectifier potassium channel can cause Jervell and Lange-Nielsen syndrome. | Tyson, J., et al. 1997. Hum Mol Genet. 6: 2179-85. PMID: 9328483
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
SPATC1L Antibody (C-4) | sc-390764 | 200 µg/ml | $322.00 | |||
SPATC1L Antibody (C-4): m-IgGκ BP-HRP Bundle | sc-523673 | 200 µg Ab, 40 µg BP | $361.00 | |||
SPATC1L Antibody (C-4): m-IgG1 BP-HRP Bundle | sc-533603 | 200 µg Ab; 20 µg BP | $361.00 | |||
SPATC1L Antibody (C-4) AC | sc-390764 AC | 500 µg/ml, 25% agarose | $424.00 | |||
SPATC1L Antibody (C-4) HRP | sc-390764 HRP | 200 µg/ml | $322.00 | |||
SPATC1L Antibody (C-4) FITC | sc-390764 FITC | 200 µg/ml | $336.00 | |||
SPATC1L Antibody (C-4) PE | sc-390764 PE | 200 µg/ml | $349.00 | |||
SPATC1L Antibody (C-4) Alexa Fluor® 488 | sc-390764 AF488 | 200 µg/ml | $364.00 | |||
SPATC1L Antibody (C-4) Alexa Fluor® 546 | sc-390764 AF546 | 200 µg/ml | $364.00 | |||
SPATC1L Antibody (C-4) Alexa Fluor® 594 | sc-390764 AF594 | 200 µg/ml | $364.00 | |||
SPATC1L Antibody (C-4) Alexa Fluor® 647 | sc-390764 AF647 | 200 µg/ml | $364.00 | |||
SPATC1L Antibody (C-4) Alexa Fluor® 680 | sc-390764 AF680 | 200 µg/ml | $364.00 | |||
SPATC1L Antibody (C-4) Alexa Fluor® 790 | sc-390764 AF790 | 200 µg/ml | $364.00 | |||
SPATC1L (C-4) Neutralizing Peptide | sc-390764 P | 100 µg/0.5 ml | $69.00 |