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SP-D Antibody (10H11) is a mouse monoclonal IgG1 antibody that detects surfactant protein D (SP-D) in human samples through western blotting (WB) and immunoprecipitation (IP) applications. Anti-SP-D antibody (10H11) recognizes a crucial component of the pulmonary surfactant system, primarily functioning as a collectin that plays a significant role in the innate immune response within the lungs. SP-D (10H11) antibody targets a protein predominantly located in the alveoli, where SP-D not only contributes to the reduction of surface tension but also acts as a first line of defense against respiratory pathogens. SP-D achieves this by binding to the lipid components of microbial cell walls, facilitating their clearance and thereby protecting the lung tissue from infection. Additionally, SP-D undergoes post-translational modifications, such as glycosylation, which are essential for stability and function, influencing SP-D′s ability to interact with pathogens and modulate immune responses. SP-D monoclonal antibody (10H11) serves as an invaluable tool for researchers studying pulmonary diseases, immune responses, and the intricate balance between surfactant function and host defense mechanisms.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
SP-D Antibody (10H11) | sc-33730 | 100 µg/ml | $316.00 |