Sox-30 Antibody (G-1): sc-390333
- Sox-30 Antibody (G-1) is a mouse monoclonal IgG2b κ Sox-30 antibody, cited in 2 publications, provided at 200 µg/ml
- specific for an epitope mapping between amino acids 56-74 near the N-terminus of Sox-30 of human origin
- Sox-30 Antibody (G-1) is recommended for detection of Sox-30 of mouse, rat, human origin by WB, IP, IF, IHC(P) and ELISA
- Anti-Sox-30 Antibody (G-1) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- TransCruz reagent for ChIP application (sc-390333 X, 200 µg/0.1 ml)
- m-IgGκ BP-HRP is the preferred secondary detection reagent for Sox-30 Antibody (G-1) for WB and IHC(P) applications. This reagent is now offered in a bundle with Sox-30 Antibody (G-1) (see ordering information below). For additional m-IgGκ BP conjugates see our complete list of Mouse IgG Binding Proteins.
Sox-30 Antibody (G-1) is a mouse monoclonal IgG2b kappa light chain antibody that detects Sox-30 protein of mouse, rat, and human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry, and enzyme-linked immunosorbent assay (ELISA). Sox-30 (G-1) antibody is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. Sox-30, also known as SRY-related HMG-box transcription factor 30, plays a crucial role in embryonic development and cell fate determination, particularly in male germ cell differentiation. Sox-30 is predominantly expressed in the testis, functioning as a transcriptional regulator by forming complexes with other proteins to influence gene expression patterns essential for male reproductive development. Sox-30 contains a high mobility group (HMG) box, a unique DNA-binding domain also found in the SRY gene, critical for sex determination. Two transcript variants encoding distinct isoforms exist for human Sox-30, highlighting the complexity and regulatory potential of this transcription factor. Sox-30 and other Sox family transcription factors are evolutionarily conserved and play significant roles in various developmental processes across different species, making Sox-30 a vital area of study in understanding developmental biology and potential implications in reproductive health.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
Sox-30 Antibody (G-1) References:
- Identification of a novel Sry-related gene and its germ cell-specific expression. | Osaki, E., et al. 1999. Nucleic Acids Res. 27: 2503-10. PMID: 10359848
- sox30: a novel zebrafish sox gene expressed in a restricted manner at the midbrain-hindbrain boundary during neurogenesis. | De Martino, SP., et al. 1999. Dev Genes Evol. 209: 357-62. PMID: 10370117
- Roles of Sox factors in neural determination: conserved signaling in evolution? | Sasai, Y. 2001. Int J Dev Biol. 45: 321-6. PMID: 11291862
- HMG-box sequences from microbats homologous to the human SOX30 HMG-box. | Bullejos, M., et al. 2000. Genetica. 110: 157-62. PMID: 11678506
- Expression of Sox transcription factors in the developing mouse pancreas. | Lioubinski, O., et al. 2003. Dev Dyn. 227: 402-8. PMID: 12815626
- Ancestry and diversity of the HMG box superfamily. | Laudet, V., et al. 1993. Nucleic Acids Res. 21: 2493-501. PMID: 8506143
- Sox10, a novel transcriptional modulator in glial cells. | Kuhlbrodt, K., et al. 1998. J Neurosci. 18: 237-50. PMID: 9412504
- Characterisation and mapping of the human SOX14 gene. | Arsic, N., et al. 1998. Cytogenet Cell Genet. 83: 139-46. PMID: 9925951
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Sox-30 Antibody (G-1) | sc-390333 | 200 µg/ml | $322.00 | |||
Sox-30 Antibody (G-1): m-IgGκ BP-HRP Bundle | sc-523494 | 200 µg Ab, 40 µg BP | $361.00 | |||
Sox-30 Antibody (G-1) X | sc-390333 X | 200 µg/0.1 ml | $322.00 | |||
Sox-30 Antibody (G-1) AC | sc-390333 AC | 500 µg/ml, 25% agarose | $424.00 | |||
Sox-30 Antibody (G-1) HRP | sc-390333 HRP | 200 µg/ml | $322.00 | |||
Sox-30 Antibody (G-1) FITC | sc-390333 FITC | 200 µg/ml | $336.00 | |||
Sox-30 Antibody (G-1) PE | sc-390333 PE | 200 µg/ml | $349.00 | |||
Sox-30 Antibody (G-1) Alexa Fluor® 488 | sc-390333 AF488 | 200 µg/ml | $364.00 | |||
Sox-30 Antibody (G-1) Alexa Fluor® 546 | sc-390333 AF546 | 200 µg/ml | $364.00 | |||
Sox-30 Antibody (G-1) Alexa Fluor® 594 | sc-390333 AF594 | 200 µg/ml | $364.00 | |||
Sox-30 Antibody (G-1) Alexa Fluor® 647 | sc-390333 AF647 | 200 µg/ml | $364.00 | |||
Sox-30 Antibody (G-1) Alexa Fluor® 680 | sc-390333 AF680 | 200 µg/ml | $364.00 | |||
Sox-30 Antibody (G-1) Alexa Fluor® 790 | sc-390333 AF790 | 200 µg/ml | $364.00 | |||
Sox-30 (G-1) Neutralizing Peptide | sc-390333 P | 100 µg/0.5 ml | $69.00 |