Soggy-1 Antibody (D-10): sc-393691
- Soggy-1 Antibody (D-10) is a mouse monoclonal IgG2a κ provided at 200 µg/ml
- specific for an epitope mapping between amino acids 21-42 at the N-terminus of Soggy-1 of mouse origin
- recommended for detection of Soggy-1 of mouse origin by WB, IP, IF and ELISA
- m-IgG Fc BP-HRP, m-IgG2a BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for Soggy-1 Antibody (D-10) for WB applications. These reagents are now offered in bundles with Soggy-1 Antibody (D-10) (see ordering information below).
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Soggy-1 Antibody (D-10) is a mouse monoclonal IgG2a antibody that detects Soggy-1 in mouse samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). Soggy-1, a secreted antagonist of the Wnt signaling pathway, plays a crucial role in regulating developmental processes, particularly in preimplantation mouse embryos and developing neural tissue, as well as in adult testis tissue. Soggy-1 monoclonal antibody (D-10) helps researchers study how Soggy-1 modulates Wnt activity, ensuring proper spatial and temporal expression of Wnt target genes, which is vital for normal embryogenesis and tissue patterning. Soggy-1 undergoes post-translational modifications, including glycosylation, which can influence stability and interaction with other proteins. The molecular weight of Soggy-1 can vary depending on the tissue and cell type, reflecting the complexity of regulation and function. Anti-Soggy-1 antibody (D-10) enables researchers to gain insights into the intricate mechanisms of Wnt signaling and its implications in developmental biology and disease.
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Soggy-1 Antibody (D-10) References:
- DkkL1 (Soggy), a Dickkopf family member, localizes to the acrosome during mammalian spermatogenesis. | Kohn, MJ., et al. 2005. Mol Reprod Dev. 71: 516-22. PMID: 15892050
- Function and biological roles of the Dickkopf family of Wnt modulators. | Niehrs, C. 2006. Oncogene. 25: 7469-81. PMID: 17143291
- Dickkopf-like1 regulates postpubertal spermatocyte apoptosis and testosterone production. | Dakhova, O., et al. 2009. Endocrinology. 150: 404-12. PMID: 18818293
- The multi-copy mouse gene Sycp3-like Y-linked (Sly) encodes an abundant spermatid protein that interacts with a histone acetyltransferase and an acrosomal protein. | Reynard, LN., et al. 2009. Biol Reprod. 81: 250-7. PMID: 19176879
- The acrosomal protein Dickkopf-like 1 (DKKL1) is not essential for fertility. | Kaneko, KJ., et al. 2010. Fertil Steril. 93: 1526-32. PMID: 19596310
- SLXL1, a novel acrosomal protein, interacts with DKKL1 and is involved in fertilization in mice. | Zhuang, XJ., et al. 2011. PLoS One. 6: e20866. PMID: 21698294
- Developmental expression and function of DKKL1/Dkkl1 in humans and mice. | Yan, Q., et al. 2012. Reprod Biol Endocrinol. 10: 51. PMID: 22817830
- Region-specific expression of Dickkopf-like1 in the adult brain. Abbreviated title: Dkkl1 in the adult brain. | Sibbe, M. and Jarowyj, J. 2013. Neurosci Lett. 535: 84-9. PMID: 23295900
- Allele-specific splicing effects on DKKL1 and ZNF419 transcripts in HeLa cells. | Martin, G., et al. 2017. Gene. 598: 107-112. PMID: 27826023
- Transcriptomic Analysis Reveals Intrinsic Abnormalities in Endometrial Polyps. | Chiu, CS., et al. 2024. Int J Mol Sci. 25: PMID: 38473810
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Soggy-1 Antibody (D-10) | sc-393691 | 200 µg/ml | $322.00 | |||
Soggy-1 Antibody (D-10): m-IgG Fc BP-HRP Bundle | sc-538284 | 200 µg Ab; 10 µg BP | $361.00 | |||
Soggy-1 Antibody (D-10): m-IgGκ BP-HRP Bundle | sc-535863 | 200 µg Ab; 40 µg BP | $361.00 | |||
Soggy-1 Antibody (D-10): m-IgG2a BP-HRP Bundle | sc-548257 | 200 µg Ab; 10 µg BP | $361.00 | |||
Soggy-1 (D-10) Neutralizing Peptide | sc-393691 P | 100 µg/0.5 ml | $69.00 |