Superoxide Dismutase 3/SOD3 Antibody (1H12): sc-58427
- Superoxide Dismutase 3/SOD3 Antibody (1H12) is a mouse monoclonal IgG2b, cited in 3 publications, provided at 100 µl
- raised against full length SOD-3 of human origin
- recommended for detection of SOD-3 of human origin by WB, IP, IF, IHC(P) and ELISA
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for Superoxide Dismutase 3/SOD3 Antibody (1H12). This work is in progress.
SOD-3 Antibody (1H12) is a mouse monoclonal IgG2b antibody that detects superoxide dismutase-3 (SOD-3) in human samples through various applications including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), and enzyme-linked immunosorbent assay (ELISA). SOD-3, also known as extracellular superoxide dismutase, plays a crucial role in protecting tissues from oxidative stress by catalyzing the dismutation of superoxide radicals into hydrogen peroxide and oxygen, thereby mitigating cellular damage caused by reactive oxygen species. SOD-3 is predominantly located in extracellular fluids such as lymph, plasma, and synovial fluid, which is vital for its function in scavenging free radicals that can lead to inflammation and tissue injury. The presence of SOD-3 in these fluids highlights its importance in maintaining redox homeostasis and protecting against oxidative damage in various physiological and pathological conditions, including cardiovascular diseases and inflammatory disorders. Anti-SOD-3 antibody (1H12) is an essential tool for researchers studying oxidative stress and its implications in human health and disease, providing reliable detection and characterization of this important enzyme.
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Superoxide Dismutase 3/SOD3 Antibody (1H12) References:
- Superoxide dismutase multigene family: a comparison of the CuZn-SOD (SOD1), Mn-SOD (SOD2), and EC-SOD (SOD3) gene structures, evolution, and expression. | Zelko, IN., et al. 2002. Free Radic Biol Med. 33: 337-49. PMID: 12126755
- SOD1, but not SOD3, deficiency accelerates diabetic renal injury in C57BL/6-Ins2(Akita) diabetic mice. | Fujita, H., et al. 2012. Metabolism. 61: 1714-24. PMID: 22632894
- SOD3 boosts T cell infiltration by normalizing the tumor endothelium and inducing laminin-α4. | Carmona-Rodríguez, L., et al. 2020. Oncoimmunology. 9: 1794163. PMID: 32934887
- Novel and Converging Ways of NOX2 and SOD3 in Trafficking and Redox Signaling in Macrophages. | Petersen, SV., et al. 2021. Antioxidants (Basel). 10: PMID: 33503855
- Binding of Equine Seminal Lactoferrin/Superoxide Dismutase (SOD-3) Complex Is Biased towards Dead Spermatozoa. | Alghamdi, AS., et al. 2022. Animals (Basel). 13: PMID: 36611662
- Uncovering SOD3 and GPX4 as new targets of Benzo[α]pyrene-induced hepatotoxicity through Metabolomics and Chemical Proteomics. | Wang, Y., et al. 2023. Redox Biol. 67: 102930. PMID: 37847980
- SOD3 regulates FLT1 to affect bone metabolism by promoting osteogenesis and inhibiting adipogenesis through PI3K/AKT and MAPK pathways. | Xu, K., et al. 2024. Free Radic Biol Med. 212: 65-79. PMID: 38141889
- Superoxide dismutase SOD-3 regulates redox homeostasis in the intestine. | Wong, CH., et al. 2023. MicroPubl Biol. 2023: PMID: 38188420
- SOD3 suppresses early cellular immune responses to parasite infection. | Li, Q., et al. 2024. Nat Commun. 15: 4913. PMID: 38851821
- Placenta-derived SOD3 deletion impairs maternal behavior via alterations in FGF/FGFR-prolactin signaling axis. | Xu, Y., et al. 2024. Cell Rep. 43: 114789. PMID: 39325622
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Superoxide Dismutase 3/SOD3 Antibody (1H12) | sc-58427 | 100 µl | $322.00 |