SNX4 Antibody (Y-36): sc-101306
- SNX4 Antibody (Y-36) is a mouse monoclonal mouse IgG2a κ κ provided at 50 µg/0.5 ml
- raised against recombinant SNX4 of human origin
- recommended for detection of SNX4 of mouse, rat and human origin by WB, IP and ELISA
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for SNX4 Antibody (Y-36). This work is in progress.
SNX4 Antibody (Y-36) is a mouse monoclonal IgG2a antibody that detects sorting nexin 4 (SNX4) in mouse, rat, and human samples through western blotting (WB), immunoprecipitation (IP), and enzyme-linked immunosorbent assay (ELISA). SNX4 plays a crucial role in intracellular trafficking and membrane dynamics, functioning as a key player in the endosomal sorting pathway. SNX4 is primarily located in the endosomes, where SNX4 interacts with various receptors, including the epidermal growth factor receptor, to facilitate their sorting and transport. This localization is vital for maintaining cellular homeostasis and regulating signaling pathways, as improper trafficking can lead to dysregulation of receptor signaling and contribute to various diseases, including cancer. SNX4 contains a phox homology (PX) domain, which is essential for interaction with phosphoinositides and other proteins, allowing participation in the formation of protein complexes that are critical for endosomal function. Additionally, SNX4 has been shown to interact with other sorting nexins, such as SNX1 and SNX2, highlighting SNX4′s role in a broader network of protein interactions that govern cellular processes. Anti-SNX4 antibody (Y-36) is an invaluable tool for researchers studying the mechanisms of intracellular trafficking and the implications of sorting nexins in health and disease.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
SNX4 Antibody (Y-36) | sc-101306 | 50 µg/0.5 ml | $316.00 |