SNX2 Antibody (13) is a mouse monoclonal IgG1 antibody that detects sorting nexin 2 (SNX2) in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), and immunofluorescence (IF). SNX2 plays a crucial role in intracellular trafficking and membrane dynamics, functioning primarily in the endosomal-lysosomal pathway where anti-SNX2 antibody (13) aids in studying the sorting and transport of various receptors, including the epidermal growth factor receptor (EGFR). SNX2 is characterized by its phox homology (PX) domain, which is essential for interaction with phosphoinositides and membrane binding, thereby facilitating recruitment to specific cellular membranes. SNX2 monoclonal antibody (13) enables research into maintaining cellular homeostasis and regulating receptor degradation, which is important for signal transduction and cellular responses to external stimuli. Dysregulation of SNX2 has been implicated in various diseases, including cancer, where altered receptor trafficking can lead to enhanced signaling pathways that promote tumor growth. SNX2 (13) antibody serves as an invaluable tool for researchers studying the mechanisms of receptor trafficking and the role of sorting nexins in cellular processes.
Ordering Information
Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
SNX2 Antibody (13) | sc-136072 | 50 µg/0.5 ml | $316.00 |