SNAT2 (h): 293T Lysate: sc-113599

SNAT2 (h): 293T Lysate is derived from the human embryonic kidney 293T cell line, which has been genetically engineered to express the human Sodium-coupled Neutral Amino Acid Transporter 2 (SNAT2). SNAT2 is an integral membrane protein that plays a crucial role in the cellular uptake of neutral amino acids, including alanine, serine, and glutamine, which are essential for various metabolic processes and cellular functions. The 293T cell line, known for its high transfection efficiency and robust protein production, is ideal for producing SNAT2 lysates. In research, SNAT2 (h): 293T Lysate is used to study the mechanisms of amino acid transport and the regulation of amino acid homeostasis in cells. SNAT2 operates through a sodium-dependent transport mechanism, where the translocation of amino acids across the plasma membrane is coupled with the transport of sodium ions. Researchers employ this lysate in biochemical assays such as Western blotting and immunoprecipitation to analyze the expression levels and post-translational modifications of SNAT2. Additionally, SNAT2 (h): 293T Lysate is valuable in functional assays to investigate the transport activity and substrate specificity of SNAT2. It is also used to study the regulation of SNAT2 expression and activity under various physiological conditions, such as nutrient availability and cellular stress. By using this lysate, researchers gain insights into the role of SNAT2 in amino acid transport and its impact on cellular metabolism and signaling pathways, advancing our understanding of nutrient sensing and metabolic regulation.