Sm G Antibody (K-15): sc-101150
- Sm G Antibody (K-15) is a mouse monoclonal IgG1 κ, cited in 1 publications, provided at 100 µg/ml
- raised against recombinant Sm G of human origin
- recommended for detection of Sm G of mouse, rat and human origin by WB, IP and ELISA
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for Sm G Antibody (K-15). This work is in progress.
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SEE ALSO...
Sm G Antibody (K-15) is a mouse monoclonal IgG1 antibody that detects Sm G in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), and enzyme-linked immunosorbent assay (ELISA). Sm G, also known as SNRPG, plays a crucial role in the formation and function of the spliceosome, a complex responsible for removing introns from pre-mRNA, which is essential for proper gene expression and regulation. Anti-Sm G antibody (K-15) targets a protein located in the nucleus, where Sm G associates with other small nuclear ribonucleoproteins (snRNPs) to form the core components of the spliceosome. This localization ensures efficient and accurate splicing, allowing for the production of mature mRNA that can be translated into functional proteins. Sm G is expressed as a 0.5 kb transcript in HeLa cells, and its gene is mapped to chromosome 2. The interaction of Sm G with other Sm proteins, such as Sm F, is critical for the stability and assembly of the snRNP complex, which underscores its importance in post-transcriptional regulation of gene expression. Sm G is a target for autoantibodies in systemic lupus erythematosus (SLE), highlighting its relevance in autoimmune diseases. Sm G monoclonal antibody (K-15) provides a valuable tool for researchers studying splicing mechanisms and the implications of splicing dysregulation in various diseases.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Sm G Antibody (K-15) | sc-101150 | 100 µg/ml | $339.00 |