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SLU7 Antibody (D-6): sc-365660

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Datasheets
  • SLU7 Antibody (D-6) is a mouse monoclonal IgM κ provided at 200 µg/ml
  • specific for an epitope mapping between amino acids 561-586 at the C-terminus of SLU7 of human origin
  • recommended for detection of SLU7 of human and avian origin by WB, IP, IF and ELISA; also reactive with additional species, including and canine, bovine, porcine and avian
  • TransCruz reagent for ChIP application (sc-365660 X, 200 µg/0.1 ml)
  • At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for SLU7 Antibody (D-6). This work is in progress.
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    SLU7 Antibody (D-6) is a mouse monoclonal IgM antibody that detects SLU7 in human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). SLU7 plays a crucial role in the mRNA splicing process, specifically during the second catalytic step where SLU7 is essential for the selection of the correct adenine-guanine (AG) dinucleotide at the 3′ splice site. This selection is vital for ensuring accurate splicing, which ultimately affects gene expression and protein synthesis. SLU7 associates with the spliceosome late in the splicing pathway, facilitating the proper positioning of exon 1 for the splicing reaction. Without SLU7, the spliceosome cannot effectively hold exon 1 in place, leading to potential errors in mRNA processing that can have significant implications for cellular function and gene regulation. Anti-SLU7 antibody (D-6) is therefore an invaluable tool for researchers studying the intricacies of mRNA splicing and its impact on gene expression in human cells.

    For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.

    Ordering Information

    Product NameCatalog #UNITPriceQtyFAVORITES

    SLU7 Antibody (D-6)

    sc-365660
    200 µg/ml
    $322.00

    SLU7 (D-6) Neutralizing Peptide

    sc-365660 P
    100 µg/0.5 ml
    $69.00

    SLU7 Antibody (D-6) X

    sc-365660 X
    200 µg/0.1 ml
    $322.00

    What application is the blocking peptide sc-365660 P appropriate for?

    Asked by: TinTin
    Thank you for your question. The blocking peptide is intended for use as a negative control, by pre-adsorbing the mouse monoclonal antibody against the antigen. For full protocol details, please contact our Technical Services Department or view our online protocol here: https://www.scbt.com/scbt/resources/protocols/peptide-neutralization
    Answered by: Technical Support
    Date published: 2017-03-01
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    Rated 5 out of 5 by from Exceptional immunofluorescence cytoplasmicExceptional immunofluorescence cytoplasmic and nuclear staining in methanol-fixed HeLa cells. -SCBT QC
    Date published: 2015-05-13
    Rated 5 out of 5 by from Great Western Blot data of SLU7 expressionGreat Western Blot data of SLU7 expression in HeLa whole cell lysate. -SCBT QC
    Date published: 2014-03-10
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    SLU7 Antibody (D-6) is rated 5.0 out of 5 by 2.
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