SLC17A4 Antibody (NQ-C19): sc-135562

SLC17A4 Antibody (NQ-C19) is a mouse monoclonal IgG1 kappa light chain antibody that detects SLC17A4 protein of human origin by western blotting (WB), immunoprecipitation (IP), and enzyme-linked immunosorbent assay (ELISA). Anti-SLC17A4 antibody (NQ-C19) is available as a non-conjugated monoclonal isotype antibody. SLC17A4 protein, also known as Solute Carrier Family 17 Member 4, is a 497 amino acid multi-pass membrane protein that plays a crucial role in the active transport of phosphate into cells via a sodium/phosphate co-transport system. This function is particularly important as phosphate is essential for various cellular processes, including energy metabolism and signaling pathways. SLC17A4 is predominantly expressed in the liver, small intestine, pancreas, and colon, highlighting its significance in nutrient absorption and metabolic regulation. Additionally, SLC17A4 shares substantial sequence identity with other members of the sodium/anion cotransporter family, such as SLC17A2 and SLC17A3, indicating potential functional similarities and interactions that may influence phosphate homeostasis in different tissues. The ability of SLC17A4 to facilitate phosphate transport underscores its importance in maintaining cellular function and overall metabolic health.

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SLC17A4 Antibody (NQ-C19) References:

1. Isolation and chromosomal mapping of a novel human gene showing homology to Na+/PO4 cotransporter.  |  Shibui, A., et al. 1999. J Hum Genet. 44: 190-2. PMID: 10319585
2. Mapping of 93 porcine ESTs preferentially expressed in liver.  |  Ponsuksili, S., et al. 2001. Mamm Genome. 12: 869-72. PMID: 11845291
3. Kinetic evidence that the Na-PO4 cotransporter is the molecular mechanism for Na/Li exchange in human red blood cells.  |  Elmariah, S. and Gunn, RB. 2003. Am J Physiol Cell Physiol. 285: C446-56. PMID: 12672655
4. Organic anion transport is the primary function of the SLC17/type I phosphate transporter family.  |  Reimer, RJ. and Edwards, RH. 2004. Pflugers Arch. 447: 629-35. PMID: 12811560

Monoclonal antibodies for mammalian and non-mammalian protein targets represent essentially all targets covered by polyclonal antibodies. Over 8,300 of our antibodies are offered as ImmunoCruz^® conjugates which eliminates the need for a secondary antibody.

Santa Cruz Biotechnology antibodies have over 360,000 research citations. Anti-SLC17A4 Antibody (NQ-C19) has 0 citations in a variety of scientific publications.

Primary antibodies like Anti-SLC17A4 Antibody (NQ-C19) for mammalian target proteins are recommended for the detection of a range of mammalian species, primarily of mouse, rat and human species. Many mammalian antibodies are also ideal for veterinary research and reactive with ovine, porcine, caprine, feline, canine, bovine and equine protein targets. Santa Cruz Biotechnology primary monoclonal antibodies are suitable for laboratory research applications and are not intended for diagnostic or therapeutic use.

SLC17A4 Antibody (NQ-C19) Specifications

Alternate Product Name: SLC17A4

Product Clone Name: NQ-C19

Classification: Primary Antibody

Clonality: Monoclonal Antibody

Antibody Isotype: IgG₁ kappa light chain

Amino Acids: 56-132

Epitope Target: SLC17A4

Epitope Species: human

Product Reactivity/Detection: SLC17A4

Species Reactivity/Detection: human

Additional Mammalian Reactivity: N/A

Additional Non-Mammalian Reactivity: N/A

Applications: WB, IP, ELISA

Vialing Information: Each vial contains 100 µg IgG₁ kappa light chain in 1.0 ml of PBS with < 0.1% sodium azide and 0.1% gelatin

Research Citations: 0 citations in various scientific publications

Available Conjugates/Forms for SLC17A4 Antibody (NQ-C19): N/A