Ski Antibody (6D763): sc-73034
- Ski Antibody (6D763) is a mouse monoclonal IgG1 κ provided at 200 µg/ml
- raised against recombinant v-Ski
- recommended for detection of Ski of mouse, rat and human origin by WB, IP and IF
- m-IgG1 BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for Ski Antibody (6D763) for WB applications. These reagents are now offered in bundles with Ski Antibody (6D763) (see ordering information below).
QUICK LINKS
Ski Antibody (6D763) is a mouse monoclonal IgG1 antibody that detects Ski in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), and immunofluorescence (IF). Ski (6D763) antibody plays a crucial role in understanding the function of Ski, which is a key regulator in the transforming growth factor-beta (TGFβ) signaling pathway. Ski is primarily located in the nucleus, where Ski forms homodimers and heterodimers, allowing Ski to bind to DNA and modulate transcriptional activity. This localization is significant because Ski effectively represses Smad activity, thereby inhibiting TGFβ-induced cell growth and extracellular matrix production. Ski′s structure includes five tandem repeats in its C-terminal domain and two leucine zipper motifs, which are essential for DNA binding capabilities and trimerization. By utilizing anti-Ski antibody (6D763), researchers can delve deeper into the mechanisms of TGFβ signaling and its implications in various cellular processes, including cancer progression and tissue fibrosis.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Ski Antibody (6D763) | sc-73034 | 200 µg/ml | $316.00 | |||
Ski Antibody (6D763): m-IgGκ BP-HRP Bundle | sc-534424 | 200 µg Ab; 40 µg BP | $354.00 | |||
Ski Antibody (6D763): m-IgG1 BP-HRP Bundle | sc-538866 | 200 µg Ab; 20 µg BP | $354.00 |