SIRP-γ Antibody (LSB2.20): sc-53604
- SIRP-γ Antibody (LSB2.20) is a mouse monoclonal IgG1 κ, cited in 3 publications, provided at 200 µg/ml
- raised against SIRP-γ-D1D2-IgG of human origin
- SIRP-gamma Antibody (LSB2.20) is recommended for detection of SIRP-γ of human origin by FCM
- Anti-SIRP-gamma Antibody (LSB2.20) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- m-IgG Fc BP-HRP and m-IgG1 BP-HRP are the preferred secondary detection reagents for SIRP-γ Antibody (LSB2.20). These reagents are now offered in bundles with SIRP-γ Antibody (LSB2.20) (see ordering information below).
SIRP-γ Antibody (LSB2.20) is a mouse monoclonal IgG1 kappa light chain antibody that detects SIRP-γ of human origin by flow cytometry (FCM). Anti-SIRP-γ antibody (LSB2.20) is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. SIRP-γ, also known as SIRP-β2 or CD172g, is a member of the signal-regulatory protein family, which plays a crucial role in modulating immune responses. SIRP-γ is predominantly expressed on T cells and a subset of B cells, where SIRP-γ functions as a negative regulator of immune signaling. CD47 interaction with SIRP-γ transmits inhibitory signals that prevent excessive immune activation, maintaining immune homeostasis. SIRP-γ′s unique structure includes an extracellular domain with immunoglobulin-like motifs, allowing for specific binding interactions essential for immune regulation. SIRP-γ′s role in immune responses has significant implications for various diseases, including cancer and autoimmune disorders, where immune activity modulation is critical.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
SIRP-γ Antibody (LSB2.20) | sc-53604 | 200 µg/ml | $322.00 | |||
SIRP-γ Antibody (LSB2.20): m-IgG Fc BP-HRP Bundle | sc-526834 | 200 µg Ab; 10 µg BP | $361.00 | |||
SIRP-γ Antibody (LSB2.20): m-IgG1 BP-HRP Bundle | sc-532207 | 200 µg Ab; 20 µg BP | $361.00 | |||
SIRP-γ Antibody (LSB2.20) AC | sc-53604 AC | 500 µg/ml, 25% agarose | $424.00 | |||
SIRP-γ Antibody (LSB2.20) HRP | sc-53604 HRP | 200 µg/ml | $322.00 | |||
SIRP-γ Antibody (LSB2.20) FITC | sc-53604 FITC | 200 µg/ml | $336.00 | |||
SIRP-γ Antibody (LSB2.20) PE | sc-53604 PE | 200 µg/ml | $349.00 | |||
SIRP-γ Antibody (LSB2.20) Alexa Fluor® 488 | sc-53604 AF488 | 200 µg/ml | $364.00 | |||
SIRP-γ Antibody (LSB2.20) Alexa Fluor® 546 | sc-53604 AF546 | 200 µg/ml | $364.00 | |||
SIRP-γ Antibody (LSB2.20) Alexa Fluor® 594 | sc-53604 AF594 | 200 µg/ml | $364.00 | |||
SIRP-γ Antibody (LSB2.20) Alexa Fluor® 647 | sc-53604 AF647 | 200 µg/ml | $364.00 | |||
SIRP-γ Antibody (LSB2.20) Alexa Fluor® 680 | sc-53604 AF680 | 200 µg/ml | $364.00 | |||
SIRP-γ Antibody (LSB2.20) Alexa Fluor® 790 | sc-53604 AF790 | 200 µg/ml | $364.00 |