SF-1 Antibody (G-12): sc-398202
- SF-1 Antibody (G-12) is a mouse monoclonal IgG1 κ, cited in 1 publications, provided at 200 µg/ml
- raised against amino acids 201-260 mapping within an internal region of SF-1 of human origin
- recommended for detection of SF-1 of human origin by WB, IP, IF and ELISA
- TransCruz reagent for ChIP application (sc-398202 X, 200 µg/0.1 ml)
- m-IgG Fc BP-HRP and m-IgG1 BP-HRP are the preferred secondary detection reagents for SF-1 Antibody (G-12) for WB applications. These reagents are now offered in bundles with SF-1 Antibody (G-12) (see ordering information below).
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SF-1 Antibody (G-12) is a mouse monoclonal IgG1 antibody that detects steroidogenic factor-1 (SF-1) in human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). SF-1 plays a crucial role in regulating multiple genes essential for adrenal and gonadal development, as well as the biosynthesis of various hormones, including adrenal and gonadal steroids, anti-Mullerian hormone (AMH), and gonadotropins. SF-1 is primarily located in the nucleus of theca/interstitial cells in the adult ovary, where SF-1 functions as a transcription factor to modulate gene expression. Nuclear localization of SF-1 is vital because SF-1 interacts directly with DNA and influences the transcription of target genes, thereby impacting hormone production and reproductive health. Anti-SF-1 antibody (G-12) is an invaluable tool for researchers studying endocrine function and disorders, providing insights into the molecular mechanisms underlying hormone regulation and reproductive biology.
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SF-1 Antibody (G-12) References:
- Steroidogenic factor 1 (SF-1) is essential for ovarian development and function. | Hanley, NA., et al. 2000. Mol Cell Endocrinol. 163: 27-32. PMID: 10963870
- Differential regulation of SF-1-cofactor interactions. | Lund, J., et al. 2002. Endocr Res. 28: 505-13. PMID: 12530655
- Molecular aspects of steroidogenic factor 1 (SF-1). | Hoivik, EA., et al. 2010. Mol Cell Endocrinol. 315: 27-39. PMID: 19616058
- Role of SF-1 and DAX-1 during differentiation of P19 cells by retinoic acid. | Teets, BW., et al. 2012. J Cell Physiol. 227: 1501-11. PMID: 21678401
- Identification of novel steroidogenic factor 1 (SF-1)-target genes and components of the SF-1 nuclear complex. | Mizutani, T., et al. 2015. Mol Cell Endocrinol. 408: 133-7. PMID: 25463758
- Enantiomer-specific activities of an LRH-1 and SF-1 dual agonist. | Mays, SG., et al. 2020. Sci Rep. 10: 22279. PMID: 33335203
- The role of steroidogenic factor 1 (SF-1) in steroidogenic cell function of the testes and ovaries of mature mice. | Smith, OE., et al. 2023. Reproduction. 165: 1-17. PMID: 36194434
- Clinical and genetic characteristics of a large international cohort of individuals with rare NR5A1/SF-1 variants of sex development. | Kouri, C., et al. 2024. EBioMedicine. 99: 104941. PMID: 38168586
- Luoshi Neiyi Prescription inhibits estradiol synthesis and inflammation in endometriosis through the HIF1A/EZH2/SF-1 pathway. | Wu, L., et al. 2024. J Ethnopharmacol. 335: 118659. PMID: 39098622
- SF-1: a key regulator of development and function in the mammalian reproductive system. | Ikeda, Y. 1996. Acta Paediatr Jpn. 38: 412-9. PMID: 8840555
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
SF-1 Antibody (G-12) | sc-398202 | 200 µg/ml | $322.00 | |||
SF-1 Antibody (G-12): m-IgG Fc BP-HRP Bundle | sc-540922 | 200 µg Ab; 10 µg BP | $361.00 | |||
SF-1 Antibody (G-12): m-IgG1 BP-HRP Bundle | sc-542465 | 200 µg Ab; 20 µg BP | $361.00 | |||
SF-1 Antibody (G-12) X | sc-398202 X | 200 µg/0.1 ml | $322.00 |