SEMA4C Antibody (37): sc-136445

SEMA4C Antibody (37) is a mouse monoclonal IgG1 kappa light chain antibody that detects SEMA4C protein of mouse, rat, human, and canine origin by western blotting (WB) and immunoprecipitation (IP). Anti-SEMA4C antibody (37) is available in both non-conjugated and various conjugated forms, including agarose and horseradish peroxidase (HRP). SEMA4C protein, also known as semaphorin-4C, is an 833 amino acid single-pass type I membrane protein characterized by a sema domain, a PSI domain, and an immunoglobulin-like C2-type domain. SEMA4C plays a crucial role in the development of neural networks by guiding the growth of neural axons through its ability to attract and repel these axons, which is essential for proper neural tissue organization. SEMA4C is expressed in various tissues, including the lung, kidney, and brain, and interacts with proteins such as GIPC and NCDN, further underscoring its importance in neural development. SEMA4C′s ability to mediate these interactions highlights its significance in both normal physiological processes and potential pathological conditions, making SEMA4C (37) monoclonal antibody a valuable tool for researchers studying neural development and related disorders.

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SEMA4C Antibody (37) References:

1. A PDZ protein regulates the distribution of the transmembrane semaphorin, M-SemF.  |  Wang, LH., et al. 1999. J Biol Chem. 274: 14137-46. PMID: 10318831
2. Sema4c, a transmembrane semaphorin, interacts with a post-synaptic density protein, PSD-95.  |  Inagaki, S., et al. 2001. J Biol Chem. 276: 9174-81. PMID: 11134026
3. Semaphorin 4C, a transmembrane semaphorin, [corrected] associates with a neurite-outgrowth-related protein, SFAP75.  |  Ohoka, Y., et al. 2001. Biochem Biophys Res Commun. 280: 237-43. PMID: 11162505
4. Identification of a member of mouse semaphorin family.  |  Inagaki, S., et al. 1995. FEBS Lett. 370: 269-72. PMID: 7656991
5. Molecular cloning and mapping of human semaphorin F from the Cri-du-chat candidate interval.  |  Simmons, AD., et al. 1998. Biochem Biophys Res Commun. 242: 685-91. PMID: 9464278

Monoclonal antibodies for mammalian and non-mammalian protein targets represent essentially all targets covered by polyclonal antibodies. Over 8,300 of our antibodies are offered as ImmunoCruz^® conjugates which eliminates the need for a secondary antibody.

Santa Cruz Biotechnology antibodies have over 360,000 research citations. Anti-SEMA4C Antibody (37) has 10 citations in a variety of scientific publications.

Primary antibodies like Anti-SEMA4C Antibody (37) for mammalian target proteins are recommended for the detection of a range of mammalian species, primarily of mouse, rat and human species. Many mammalian antibodies are also ideal for veterinary research and reactive with ovine, porcine, caprine, feline, canine, bovine and equine protein targets. Santa Cruz Biotechnology primary monoclonal antibodies are suitable for laboratory research applications and are not intended for diagnostic or therapeutic use.

SEMA4C Antibody (37) Specifications

Alternate Product Name: SEMA4C

Product Clone Name: 37

Classification: Primary Antibody

Clonality: Monoclonal Antibody

Antibody Isotype: IgG₁ kappa light chain

Amino Acids: 400-510

Epitope Target: SEMA4C

Epitope Species: human

Product Reactivity/Detection: SEMA4C

Species Reactivity/Detection: mouse, rat, human, canine

Additional Mammalian Reactivity: N/A

Additional Non-Mammalian Reactivity: N/A

Applications: WB, IP

Vialing Information: Each vial contains 200 µg IgG₁ kappa light chain in 1.0 ml of PBS with < 0.1% sodium azide and 0.1% gelatin

Research Citations: 10 citations in various scientific publications

Available Conjugates/Forms for SEMA4C Antibody (37): AC: Agarose, HRP: Horseradish Peroxidase