Sec31A Antibody (32): sc-136233
- Sec31A Antibody (32) is a mouse monoclonal IgG1, cited in 2 publications, provided at 50 µg/0.5 ml
- raised against amino acids 522-719 of Sec31A of human origin
- recommended for detection of Sec31A of human origin by WB, IP and IF
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for Sec31A Antibody (32). This work is in progress.
Sec31A Antibody (32) is a mouse monoclonal IgG1 antibody that detects Sec31A in human samples through applications such as western blotting (WB), immunoprecipitation (IP), and immunofluorescence (IF). Sec31A, also known as ABP125, ABP130, or SEC31L1, is a crucial 1,220 amino acid protein characterized by the presence of seven WD repeats, which contribute to a unique tertiary propeller structure. This structural feature facilitates Sec31A′s role in the COP II (coat protein II) complex, essential for transport vesicle formation from the endoplasmic reticulum (ER). By promoting cargo molecule selection, Sec31A plays a vital role in intracellular transport processes, ensuring proteins and lipids are correctly delivered to their destinations within the cell. High-level ubiquitous expression of Sec31A underscores its importance in cellular function, while chromosomal aberrations involving the Sec31A gene have been linked to inflammatory myofibroblastic tumors, indicating potential involvement in carcinogenesis. Multiple isoforms of Sec31A due to alternative splicing events highlight the complexity and regulatory potential in various biological contexts. anti-Sec31A antibody (32) serves as an invaluable tool for researchers investigating vesicular trafficking dynamics and Sec31A implications in health and disease.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Sec31A Antibody (32) | sc-136233 | 50 µg/0.5 ml | $316.00 |