Date published: 2025-10-6

1-800-457-3801

SCBT Portrait Logo
Seach Input

Sec61 α Antibodies

Santa Cruz Biotechnology offers a broad range of Sec61 α Antibodies for investigating protein translocation and membrane biogenesis mechanisms. Sec61 α Antibodies are validated for multiple applications, including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), flow cytometry (FCM), and enzyme-linked immunosorbent assay (ELISA). Sec61 α is a central component of the Sec61 translocon, facilitating nascent polypeptide translocation across the endoplasmic reticulum membrane. Sec61 α maintains cellular homeostasis through its essential role in secretory and membrane protein function. Research focused on Sec61 α continues to reveal new insights about cellular processes and disease mechanisms. Understanding Sec61 α dynamics advances knowledge in cell biology, protein trafficking, and membrane transport. Investigating Sec61 α function helps illuminate its role in both normal physiology and pathological conditions. Researchers can leverage molecular tools to explore complex biological questions about protein translocation pathways. Santa Cruz Biotechnology monoclonal antibodies for Sec61 α support scientists in making meaningful contributions to protein transport and cellular biology research.

SEE ALSO...

Sec61 α Antibodies

Empty Table HeaderProduct NameCATALOG #ISOTYPEEPITOPEAPPLICATIONSSpeciesCitationsRATING

Sec61α Antibody (G-2)

sc-393182mouse IgG1 κ392-423 (h)WB, IP, IF, IHC(P), ELISAm, r, h
7
(9)

Sec61 α CRISPR Knockout, HDR and Double Nickase Plasmids

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

Sec61α1 CRISPR/Cas9 KO Plasmid (h)

sc-402222hGene KnockoutGFP0
(0)

Sec61α1 HDR Plasmid (h)

sc-402222-HDRhHomology Directed RepairPuromycin0
(0)

Sec61α1 Double Nickase Plasmid (h)

sc-402222-NIChGene KnockoutPuromycin0
(0)

Sec61α1 Double Nickase Plasmid (h2)

sc-402222-NIC-2hGene KnockoutPuromycin0
(0)

Sec61α1 CRISPR/Cas9 KO Plasmid (m)

sc-424716mGene KnockoutGFP0
(0)

Sec61α1 HDR Plasmid (m)

sc-424716-HDRmHomology Directed RepairPuromycin0
(0)

Sec61α1 Double Nickase Plasmid (m)

sc-424716-NICmGene KnockoutPuromycin0
(0)

Sec61α1 Double Nickase Plasmid (m2)

sc-424716-NIC-2mGene KnockoutPuromycin0
(0)

Sec61α2 CRISPR/Cas9 KO Plasmid (h)

sc-402223hGene KnockoutGFP0
(0)

Sec61α2 HDR Plasmid (h)

sc-402223-HDRhHomology Directed RepairPuromycin0
(0)

Sec61α2 Double Nickase Plasmid (h)

sc-402223-NIChGene KnockoutPuromycin0
(0)

Sec61α2 Double Nickase Plasmid (h2)

sc-402223-NIC-2hGene KnockoutPuromycin0
(0)

Sec61α2 CRISPR/Cas9 KO Plasmid (m)

sc-425419mGene KnockoutGFP0
(0)

Sec61α2 HDR Plasmid (m)

sc-425419-HDRmHomology Directed RepairPuromycin0
(0)

Sec61α2 Double Nickase Plasmid (m)

sc-425419-NICmGene KnockoutPuromycin0
(0)

Sec61α2 Double Nickase Plasmid (m2)

sc-425419-NIC-2mGene KnockoutPuromycin0
(0)

Sec61 α CRISPR Activation Products

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

Sec61α1 CRISPR Activation Plasmid (h)

sc-402222-ACThGene ActivationPuro, Blast, Hygro0
(0)

Sec61α1 CRISPR Activation Plasmid (h2)

sc-402222-ACT-2hGene ActivationPuro, Blast, Hygro0
(0)

Sec61α1 Lentiviral Activation Particles (h)

sc-402222-LAChGene ActivationPuro, Blast, Hygro0
(0)

Sec61α1 Lentiviral Activation Particles (h2)

sc-402222-LAC-2hGene ActivationPuro, Blast, Hygro0
(0)

Sec61α1 CRISPR Activation Plasmid (m)

sc-424716-ACTmGene ActivationPuro, Blast, Hygro0
(0)

Sec61α1 CRISPR Activation Plasmid (m2)

sc-424716-ACT-2mGene ActivationPuro, Blast, Hygro0
(0)

Sec61α1 Lentiviral Activation Particles (m)

sc-424716-LACmGene ActivationPuro, Blast, Hygro0
(0)

Sec61α1 Lentiviral Activation Particles (m2)

sc-424716-LAC-2mGene ActivationPuro, Blast, Hygro0
(0)

Sec61α2 CRISPR Activation Plasmid (h)

sc-402223-ACThGene ActivationPuro, Blast, Hygro0
(0)

Sec61α2 CRISPR Activation Plasmid (h2)

sc-402223-ACT-2hGene ActivationPuro, Blast, Hygro0
(0)

Sec61α2 Lentiviral Activation Particles (h)

sc-402223-LAChGene ActivationPuro, Blast, Hygro0
(0)

Sec61α2 Lentiviral Activation Particles (h2)

sc-402223-LAC-2hGene ActivationPuro, Blast, Hygro0
(0)

Sec61α2 CRISPR Activation Plasmid (m)

sc-425419-ACTmGene ActivationPuro, Blast, Hygro0
(0)

Sec61α2 CRISPR Activation Plasmid (m2)

sc-425419-ACT-2mGene ActivationPuro, Blast, Hygro0
(0)

Sec61α2 Lentiviral Activation Particles (m)

sc-425419-LACmGene ActivationPuro, Blast, Hygro0
(0)

Sec61α2 Lentiviral Activation Particles (m2)

sc-425419-LAC-2mGene ActivationPuro, Blast, Hygro0
(0)

Sec61 α siRNA, shRNA Plasmid and shRNA Lentiviral Particle Gene Silencers

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

Sec61α1 siRNA (h)

sc-41284hGene SilencingN/A0
(0)

Sec61α1 shRNA Plasmid (h)

sc-41284-SHhGene SilencingPuromycin0
(0)

Sec61α1 shRNA (h) Lentiviral Particles

sc-41284-VhGene SilencingPuromycin0
(0)

Sec61α1 siRNA (m)

sc-41285mGene SilencingN/A0
(0)

Sec61α1 shRNA Plasmid (m)

sc-41285-SHmGene SilencingPuromycin0
(0)

Sec61α1 shRNA (m) Lentiviral Particles

sc-41285-VmGene SilencingPuromycin0
(0)

Sec61α2 siRNA (h)

sc-106541hGene SilencingN/A0
(0)

Sec61α2 shRNA Plasmid (h)

sc-106541-SHhGene SilencingPuromycin0
(0)

Sec61α2 shRNA (h) Lentiviral Particles

sc-106541-VhGene SilencingPuromycin0
(0)

Sec61α2 siRNA (m)

sc-153318mGene SilencingN/A0
(0)

Sec61α2 shRNA Plasmid (m)

sc-153318-SHmGene SilencingPuromycin0
(0)

Sec61α2 shRNA (m) Lentiviral Particles

sc-153318-VmGene SilencingPuromycin0
(0)