SEB Antibody (S643): sc-52229

SEB Antibody (S643) is a mouse monoclonal IgG1 antibody that detects Staphylococcus enterotoxin B (SEB) of Staphylococcus aureus by enzyme-linked immunosorbent assay (ELISA). Anti-SEB antibody (S643) plays a crucial role in research related to foodborne illnesses caused by Staphylococcus aureus, as SEB antibody (S643) targets a potent bacterial superantigen known for its ability to activate T cells and induce a robust immune response. The structure of Staphylococcus enterotoxin B is particularly significant, as SEB consists of a single-chain polypeptide with a unique disulfide bond that stabilizes its conformation. This structural feature is essential for its function, allowing Staphylococcus enterotoxin B to effectively bind to major histocompatibility complex (MHC) class II molecules and T cell receptors, leading to the activation of a large number of T cells. The resulting cytokine storm can cause severe symptoms, including high fever and shock, making the study of Staphylococcus enterotoxin B and its interactions vital for understanding the mechanisms of food poisoning and developing potential therapeutic strategies. SEB antibody (S643) is an invaluable tool for researchers investigating the pathogenicity of Staphylococcus aureus and the immunological responses SEB elicits.

The preferred SEB antibody is SEB Antibody (2B33): sc-73351.