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SEB Antibody (S222) is a mouse monoclonal IgG1 antibody that detects Staphylococcus enterotoxin B (SEB) of Staphylococcus aureus by enzyme-linked immunosorbent assay (ELISA). Anti-SEB antibody (S222) plays a crucial role in research related to foodborne illnesses caused by Staphylococcus aureus, as SEB antibody (S222) targets a potent bacterial superantigen known for its ability to activate T cells and induce a robust immune response. The structure of Staphylococcus enterotoxin B is particularly significant, consisting of a single chain polypeptide with a unique disulfide bond that stabilizes its conformation. This structural feature is essential for function, allowing Staphylococcus enterotoxin B to effectively bind to T cell receptors and major histocompatibility complex (MHC) class II molecules, leading to the activation of numerous T cells. The resulting cytokine storm can cause severe symptoms, including high fever and shock, making SEB (S222) monoclonal antibody an invaluable tool for researchers investigating the pathogenic effects of Staphylococcus enterotoxin B and its role in immune system modulation.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
SEB Antibody (S222) | sc-52228 | 100 µg/ml | $322.00 |