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SEA Antibody (E8) is a mouse monoclonal IgG1 antibody that detects Staphylococcus enterotoxin A of Staphylococcus aureus by western blotting (WB). Anti-SEA antibody (E8) plays a crucial role in research related to foodborne illnesses caused by Staphylococcus aureus, a bacterium known for producing enterotoxins that can lead to severe gastrointestinal distress and systemic effects. Staphylococcus enterotoxin A is a single-chain polypeptide characterized by a unique structure that includes a disulfide bond formed by two half cystines, which is essential for stability and biological activity. This structural integrity enables Staphylococcus enterotoxin A to effectively bind to class II major histocompatibility complex (MHC) molecules, facilitating T cell activation and interleukin-2 release. The interaction between Staphylococcus enterotoxin A and T cell receptors is a key mechanism in the immune response, highlighting the importance of understanding this protein′s structure for developing therapeutic strategies against food poisoning and related immune disorders. SEA monoclonal antibody (E8) serves as an invaluable tool for researchers investigating the pathogenic mechanisms of Staphylococcus aureus and the role of enterotoxins in human health.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
SEA Antibody (E8) | sc-66133 | 100 µg/ml | $316.00 |