Se51.9 Antibody (F-2): sc-377239
- Se51.9 Antibody (F-2) is a mouse monoclonal IgG2b κ Se51.9 antibody, cited in 1 publications, provided at 200 µg/ml
- raised against amino acids 1-237 representing full length Se51.9 of Streptococcus equi subsp. equi origin
- Se51.9 Antibody (F-2) is recommended for detection of Surface protein Se46.8 of Streptococcus equi subsp. equi 4047 and Streptococcus equi subsp. zooepidemicus MGCS10565 origin of and S. equi origin by WB, IP, IF and ELISA
- Anti-Se51.9 Antibody (F-2) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- m-IgGκ BP-HRP is the preferred secondary detection reagent for Se51.9 Antibody (F-2) for WB applications. This reagent is now offered in a bundle with Se51.9 Antibody (F-2) (see ordering information below). For additional m-IgGκ BP conjugates see our complete list of Mouse IgG Binding Proteins.
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Se51.9 Antibody (F-2) is a mouse monoclonal IgG2b kappa light chain antibody that detects Se51.9 protein of S. equi origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). Se51.9 monoclonal antibody (F-2) is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. Se51.9, also known as surface protein Se51.9, consists of 237 amino acids and plays a crucial role in the pathogenesis of Streptococcus equi by facilitating adherence to host tissues, which is essential for colonization and infection. Understanding Se51.9 function is vital for developing targeted therapies and vaccines against equine strangles, a disease caused by S. equi. Se51.9′s ability to interact with host cell receptors underscores its importance in the bacterial lifecycle and highlights Se51.9′s potential as a target for therapeutic intervention.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
Se51.9 Antibody (F-2) References:
- Getting to grips with strangles: an effective multi-component recombinant vaccine for the protection of horses from Streptococcus equi infection. | Guss, B., et al. 2009. PLoS Pathog. 5: e1000584. PMID: 19763180
- Molecular characterisation of 'strangles' outbreaks in the UK: the use of M-protein typing of Streptococcus equi ssp. equi. | Ivens, PA., et al. 2011. Equine Vet J. 43: 359-64. PMID: 21492215
- Association of Streptococcus equi with equine monocytes. | Mérant, C., et al. 2011. Vet Immunol Immunopathol. 143: 83-6. PMID: 21752476
- Streptococcus equi: a pathogen restricted to one host. | Waller, AS., et al. 2011. J Med Microbiol. 60: 1231-1240. PMID: 21757503
- Streptococcus equi subspecies equi infection (strangles) in horses. | Boyle, A. 2011. Compend Contin Educ Vet. 33: E1-7; quiz E8. PMID: 21870348
- Development of a novel mucosal vaccine against strangles by supercritical enhanced atomization spray-drying of Streptococcus equi extracts and evaluation in a mouse model. | Rodrigues, MA., et al. 2012. Eur J Pharm Biopharm. 82: 392-400. PMID: 22841882
- Detection of Streptococcus equi subspecies equi using a triplex qPCR assay. | Webb, K., et al. 2013. Vet J. 195: 300-4. PMID: 22884566
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Se51.9 Antibody (F-2) | sc-377239 | 200 µg/ml | $322.00 | |||
Se51.9 Antibody (F-2): m-IgGκ BP-HRP Bundle | sc-523247 | 200 µg Ab, 40 µg BP | $361.00 | |||
Se51.9 Antibody (F-2) AC | sc-377239 AC | 500 µg/ml, 25% agarose | $424.00 | |||
Se51.9 Antibody (F-2) HRP | sc-377239 HRP | 200 µg/ml | $322.00 | |||
Se51.9 Antibody (F-2) FITC | sc-377239 FITC | 200 µg/ml | $336.00 | |||
Se51.9 Antibody (F-2) PE | sc-377239 PE | 200 µg/ml | $349.00 | |||
Se51.9 Antibody (F-2) Alexa Fluor® 488 | sc-377239 AF488 | 200 µg/ml | $364.00 | |||
Se51.9 Antibody (F-2) Alexa Fluor® 546 | sc-377239 AF546 | 200 µg/ml | $364.00 | |||
Se51.9 Antibody (F-2) Alexa Fluor® 594 | sc-377239 AF594 | 200 µg/ml | $364.00 | |||
Se51.9 Antibody (F-2) Alexa Fluor® 647 | sc-377239 AF647 | 200 µg/ml | $364.00 | |||
Se51.9 Antibody (F-2) Alexa Fluor® 680 | sc-377239 AF680 | 200 µg/ml | $364.00 | |||
Se51.9 Antibody (F-2) Alexa Fluor® 790 | sc-377239 AF790 | 200 µg/ml | $364.00 |