Salmonella O Antibody (10D9H): sc-52221

Salmonella O Antibody (10D9H) is a mouse monoclonal IgG1 kappa light chain antibody that detects the Salmonella O protein of Salmonella paratyphi, Salmonella typhimurium, Salmonella enteriditis, Salmonella anatum, and Salmonella selandia by immunofluorescence (IF). Anti-Salmonella O antibody (10D9H) is available as a non-conjugated format. Salmonella O protein plays a crucial role in the pathogenicity of Salmonella species, as this component of the somatic O antigen is essential for bacterial evasion of host immune responses. O antigen, a surface polysaccharide, consists of repeating oligosaccharide units and varies among different Salmonella serotypes, contributing to classification and virulence. This diversity in O antigen structure influences bacterial resistance to complement-mediated lysis, enhancing survival in hosts. Understanding Salmonella O protein function and variability remains vital for developing targeted therapies and vaccines against Salmonella infections, which can cause typhoid fever and foodborne illnesses.

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Salmonella O Antibody (10D9H) References:

1. Permanent intraperitoneal defogging of the optics during laparoscopy.  |  Jakubowski, A. 1977. Obstet Gynecol. 49: 128. PMID: 137372
2. Molecular and functional characterization of O antigen transfer in Vibrio cholerae.  |  Schild, S., et al. 2005. J Biol Chem. 280: 25936-47. PMID: 15908430
3. Altering the length of the lipopolysaccharide O antigen has an impact on the interaction of Salmonella enterica serovar Typhimurium with macrophages and complement.  |  Murray, GL., et al. 2006. J Bacteriol. 188: 2735-9. PMID: 16547065
4. The PmrA/PmrB and RcsC/YojN/RcsB systems control expression of the Salmonella O-antigen chain length determinant.  |  Delgado, MA., et al. 2006. Mol Microbiol. 60: 39-50. PMID: 16556219
5. Sensitive titration microcalorimetric study of the binding of Salmonella O-antigenic oligosaccharides by a monoclonal antibody.  |  Sigurskjold, BW., et al. 1991. Eur J Biochem. 197: 239-46. PMID: 1707812
6. Characterisation of the Salmonella O:8 antigen in the O-chain of the lipopolysaccharide produced by Salmonella virginia O:8.  |  MacLean, LL. and Perry, MB. 1991. Biochem Cell Biol. 69: 852-8. PMID: 1726362
7. Preliminary crystal structure analysis of an Fab specific for a Salmonella O-polysaccharide antigen.  |  Rose, DR., et al. 1990. J Mol Biol. 215: 489-92. PMID: 2231716
8. Evolution of Salmonella O antigen variation by interspecific gene transfer on a large scale.  |  Reeves, P. 1993. Trends Genet. 9: 17-22. PMID: 8434412
9. Interactions of phage P22 tails with their cellular receptor, Salmonella O-antigen polysaccharide.  |  Baxa, U., et al. 1996. Biophys J. 71: 2040-8. PMID: 8889178

Monoclonal antibodies for mammalian and non-mammalian protein targets represent essentially all targets covered by polyclonal antibodies. Over 8,300 of our antibodies are offered as ImmunoCruz^® conjugates which eliminates the need for a secondary antibody.

Santa Cruz Biotechnology antibodies have over 360,000 research citations. Anti-Salmonella O Antibody (10D9H) has 1 citations in a variety of scientific publications.

Primary antibodies for mammalian target proteins are recommended for the detection of a range of mammalian species, primarily of mouse, rat and human species. Many mammalian antibodies are also ideal for veterinary research and reactive with ovine, porcine, caprine, feline, canine, bovine and equine protein targets. Santa Cruz Biotechnology primary monoclonal antibodies are suitable for laboratory research applications and are not intended for diagnostic or therapeutic use.

Salmonella O Antibody (10D9H) Specifications

Alternate Product Name: Salmonella O

Product Clone Name: 10D9H

Classification: Primary Antibody

Clonality: Monoclonal Antibody

Antibody Isotype: mouse IgG₁ κ kappa light chain

Amino Acids:

Epitope Target: Salmonella O

Epitope Species: Salmonella enteriditis, Salmonella paratyphi and Salmonella typhimurium

Product Reactivity/Detection: Salmonella enteriditis, paratyphi and typhimurium, anatum and selandia

Species Reactivity/Detection: Salmonella paratyphi, Salmonella typhimurium, Salmonella enteriditis, Salmonella anatum, and Salmonella selandia

Additional Mammalian Reactivity: N/A

Additional Non-Mammalian Reactivity: N/A

Applications: IF

Vialing Information: Each vial contains 100 µg IgG₁ kappa light chain in 1.0 ml of PBS with < 0.1% sodium azide and 0.1% gelatin

Research Citations: 1 citations in various scientific publications

Available Conjugates/Forms for Salmonella O Antibody (10D9H): N/A