Date published: 2025-10-15

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S-Butyrylthiocholine Iodide (CAS 1866-16-6)

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Alternate Names:
(2-Mercaptoethyl)trimethylammonium iodide butyrate
Application:
S-Butyrylthiocholine Iodide is a chromogenic substrate for cholinesterases
CAS Number:
1866-16-6
Purity:
≥97%
Molecular Weight:
317.23
Molecular Formula:
C9H20INOS
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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S-Butyrylthiocholine Iodide is primarily employed in biochemical research for its role as a substrate in the assay of cholinesterase enzymes, which are key in nervous system function by breaking down acetylcholine. This usage facilitates the study of enzyme kinetics and the mechanism of enzyme action, providing valuable insights into the regulation of neurotransmitter levels and nerve signal transmission. Research involving S-Butyrylthiocholine Iodide includes investigations into the effects of inhibitors on cholinesterase activity, which is for understanding conditions characterized by abnormal neurotransmitter degradation. Additionally, it is used in studies focused on pesticide and nerve agent exposure, where cholinesterase activity is a critical marker for toxicological assessment. The compound also serves in comparative studies among different species to elucidate evolutionary variations in cholinesterase activity.


S-Butyrylthiocholine Iodide (CAS 1866-16-6) References

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  3. Characterization of cholinesterases in plasma of three Portuguese native bird species: application to biomonitoring.  |  Santos, CS., et al. 2012. PLoS One. 7: e33975. PMID: 22470503
  4. Characterization of plasma cholinesterase from the White stork (Ciconia ciconia) and its in vitro inhibition by anticholinesterase pesticides.  |  Oropesa, AL., et al. 2013. Ecotoxicol Environ Saf. 97: 131-8. PMID: 23962622
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  8. New Insights into Butyrylcholinesterase Activity Assay: Serum Dilution Factor as a Crucial Parameter.  |  Jońca, J., et al. 2015. PLoS One. 10: e0139480. PMID: 26444431
  9. Determination of butyrylcholinesterase activity based on thiamine luminescence modulated by MnO2 nanosheets.  |  Qu, Z., et al. 2021. Talanta. 224: 121831. PMID: 33379049
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Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

S-Butyrylthiocholine Iodide, 5 g

sc-286740
5 g
$59.00

S-Butyrylthiocholine Iodide, 50 g

sc-286740A
50 g
$587.00

S-Butyrylthiocholine Iodide, 100 g

sc-286740B
100 g
$959.00

S-Butyrylthiocholine Iodide, 500 g

sc-286740C
500 g
$3927.00