Date published: 2026-1-8

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BChE Substrates

Santa Cruz Biotechnology now offers a broad range of BChE Substrates for use in various applications. BChE (butyrylcholinesterase) substrates are essential tools in scientific research, particularly in the study of enzyme kinetics, neurobiology, and toxicology. BChE is a serine hydrolase enzyme that hydrolyzes choline-based esters, playing a critical role in the metabolism of various compounds, including drugs and toxins. By providing specific substrates for BChE, researchers can investigate the enzyme's activity under different conditions, explore its substrate specificity, and study the regulation of cholinergic signaling pathways. These substrates are invaluable in experiments aimed at understanding the role of BChE in the breakdown of acetylcholine, a neurotransmitter involved in muscle activation and various neural processes. Additionally, BChE substrates are used in toxicological studies to assess the enzyme's role in detoxifying organophosphates and other cholinesterase inhibitors, which are commonly found in pesticides and nerve agents. The use of these substrates extends to research, where they are employed to screen for potential inhibitors or activators of BChE, providing insights into the enzyme's potential in conditions where cholinergic signaling is dysregulated. The availability of a wide range of BChE substrates allows researchers to design experiments that are precisely tailored to their specific research needs, advancing our understanding of BChE function and its broader implications in biochemistry and neurobiology. View detailed information on our available BChE Substrates by clicking on the product name.

SEE ALSO...

Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

S-Butyrylthiocholine Iodide

1866-16-6sc-286740
sc-286740A
sc-286740B
sc-286740C
5 g
50 g
100 g
500 g
$60.00
$599.00
$978.00
$4006.00
(0)

S-Butyrylthiocholine Iodide exhibits unique reactivity as a substrate for butyrylcholinesterase (BChE), characterized by its thioester bond which enhances nucleophilic attack by the enzyme. This interaction leads to rapid hydrolysis, generating thiocholine and butyric acid. The compound's structural features promote specific conformational changes in BChE, influencing catalytic efficiency and reaction kinetics. Its ionic nature also affects solubility and diffusion in biological systems, impacting enzyme-substrate dynamics.

Butyrylcholine chloride

2963-78-2sc-255007
sc-255007A
10 g
25 g
$55.00
$141.00
(0)

Butyrylcholine chloride serves as a potent substrate for butyrylcholinesterase (BChE), distinguished by its quaternary ammonium structure that facilitates strong ionic interactions with the enzyme's active site. This interaction accelerates hydrolysis, yielding choline and butyric acid. The compound's hydrophilic characteristics enhance its solubility in aqueous environments, influencing the rate of enzymatic reactions and the overall kinetics of substrate turnover. Its unique molecular configuration also affects the enzyme's conformational stability during catalysis.